OBJECTIVE: This study compared the load-deflection ratios between 0.019 x 0.025-in rectangular orthodontic wires using 5 conventional preformed nickel-titanium (NiTi) and 5 heat-activated NiTi archwires from four different manufacturers (Abzil, Morelli, 3M Unitek and Ormco), totaling 40 archwires. The archwires were placed in typodonts without tooth # 11 and tested using a universal testing machine connected to a computer. RESULTS: The comparisons of mean load-deflection values of conventional NiTi wires revealed that the lowest mean-deflection ratio was found for 3M Unitek, followed by Ormco, Morelli and Abzil. Regarding the heat-activated wires, the lowest load-deflection ratio was found for Ormco, followed by 3M Unitek, Abzil, and Morelli. CONCLUSION: The comparison of mean load-deflection ratios revealed that the heat-activated wires had lowest mean load-deflection ratios, and this trend was seen during all the study. However, at 2-mm deflection, mean load-deflection ratios for heat-activated Morelli and conventional 3M Unitek wires were very similar, and this difference was not statistically significant
Background: The application of static compressive forces to periodontal ligament fibroblasts (PDLFs) in vivo or in vitro has been linked to the expression of biochemical agents and local tissue modifications that could be involved in maintaining homeostasis during orthodontic movement. An approach used for identifying mesenchymal cells, or a subpopulation of progenitor cells in both tumoral and normal tissues, involves determining the activity of aldehyde dehydrogenase (ALDH). However, the role of subpopulations of PDLF-derived undifferentiated cells in maintaining homeostasis during tooth movement remains unclear. Objective: This study aimed at analyzing the effect of applying a static compressive force to PDLFs on the activity of ALDH in these cells. Methods: PDLFs were distributed into two groups: control group (CG), where fibroblasts were not submitted to compression, and experimental group (EG), where fibroblasts were submitted to a static compressive force of 4 g/mm2 for 6 hours. The compressive force was applied directly to the cells using a custom-built device. ALDH activity in the PDLFs was evaluated by a flow cytometry assay. Results: ALDH activity was observed in both groups, but was significantly lower in EG than in CG after the application of a static compressive force in the former. Conclusion: Application of a static compressive force to PDLFs decreased ALDH activity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.