Naringenin enhances antitumor effect of doxorubicin by selective modulating drug efflux pathways. Naringenin will be a useful adjunct to improve the effectiveness of chemotherapeutic agents in treatment of human cancers.
A new constitutive model for semi-solid composites forming was derived with analyzing constitutive relationships of semi-solid metal and composites forming. Parameters in the constitutive model were determined by the multiple nonlinear regression method. A constitutive relationship of semi-solid SiCp/AZ61 composites thixotropic plastic forming was proposed. The calculated results were good agreement with the experimental ones. The proposed constitutive model has the higher forecast precision and practical significance. The construction of constitutive model provides references for the thixotropic forming theory, simulation and technology.
The microstructural evolution of AZ61 semi-solid magnesium alloy during semi-solid
remelting process was studied in this paper. The semi-solid billet was fabricated by strain-induced
melt activation (SIMA) method. The results showed that the initial semi-solid grains melt mainly
through coalescence. With the prolongation of isothermal holding time, the grains grew up and
spheroidized, in which the mean diameter of grain and liquid volume fraction increased. In the
meantime, the higher the holding temperature, the faster the grain grew and spheroidized. The
suitable reheating temperature of AZ61 semi-solid magnesium alloy was 592. The samples were
susceptible to serious deformation beyond 597.
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