This paper describes a nanoporous substrate for applications in biomedical diagnostics. A
photolithographic microstructuring technique for an ordered nanopore array fabrication is
reported. The process uses a negative resist with hydrophobic properties increasing
specificity to biomolecule linking. Nanoporous alumina is formed by an anodic process and
yields straight holes with high aspect ratio: its use as substrates for DNA-microarray or
protein-chip application offers several advantages over conventional supports, making them
very attractive to use as supports for biological sample microarray application.
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