The insecticide activity of synthetic pyrethroids to Triatoma infestans was tested by topical application. Deltamethrin, fenpropathrin, bioresmethrin, permethrin, cypermethrin, d-phenothrin and cyphenothrin showed the highest activity.The susceptibility to poisoning of adult insects by these pyrethroids (except bioresmethrin) was increased by cotreatment with profenofos or with piperonyl butoxide (PBO). Assayed pyrethroids synergized by PBO showed similar general structure.The vinyl cyano pyrethroids showed a knockdown effect with a delayed recovery. During 15 days after intoxication with deltamethrin, insect recovery was observed. Recovery blockage by PBO was observed in cyphenothrin and deltamethrin poisoning at low doses.Resume-L'activite insecticide de pyrethrinoides de synthese a ete essayee par application topique sur Triatoma infestans.Deltamethrine, fenpropathrine, bioresmethrine, permethrine, cypermethrine, d-phenothrine et cyphenothrine ont montree la meilleure activite.La susceptibilite a l'intoxication par ces pyrethrinoides des insectes adultes (avec l'exception de bioresmethrine) a ete amelioree en ajoutant le profenofos ou le butoxide de piperonyl (PBO) dans les traitements. Les pyrethrinoides synergisees par PBO ont montree une structure chimique similaire. Les vinyl cyano pirethrinoides ont montree l'effect choc accompagne d'une recuperation retardee. Pendant 15 jours apres l'intoxication avec la deltamethrine, la recuperation des insectes a ete obtenue.
The presence of an acetylcholinesterase inhibitor in the compound eyes of adult Triatoma infestans was demonstrated. The inhibitory activity was localized in the ocular pigments separated by disc gel electrophoresis. The inhibitor was selective against insect acetylcholinesterase, reversible, noncompetitive and heart stable.
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