Cardiovascular diseases are among the most common serious illnesses affecting human health. CVDs may be prevented or mitigated by early diagnosis, and this may reduce mortality rates. Identifying risk factors using machine learning models is a promising approach. We would like to propose a model that incorporates different methods to achieve effective prediction of heart disease. For our proposed model to be successful, we have used efficient Data Collection, Data Pre-processing and Data Transformation methods to create accurate information for the training model. We have used a combined dataset (Cleveland, Long Beach VA, Switzerland, Hungarian and Stat log). Suitable features are selected by using the Relief, and Least Absolute Shrinkage and Selection Operator (LASSO) techniques. New hybrid classifiers like Decision Tree Bagging Method (DTBM), Random Forest Bagging Method (RFBM), K-Nearest Neighbors Bagging Method (KNNBM), AdaBoost Boosting Method (ABBM), and Gradient Boosting Boosting Method (GBBM) are developed by integrating the traditional classifiers with bagging and boosting methods, which are used in the training process. We have also instrumented some machine learning algorithms to calculate the Accuracy (ACC), Sensitivity (SEN), Error Rate, Precision (PRE) and F1 Score (F1) of our model, along with the Negative Predictive Value (NPR), False Positive Rate (FPR), and False Negative Rate (FNR). The results are shown separately to provide comparisons. Based on the result analysis, we can conclude that our proposed model produced the highest accuracy while using RFBM and Relief feature selection methods (99.05%).

COVID-19, regarded as the deadliest virus of the 21st century, has claimed the lives of millions of people around the globe in less than two years. Since the virus initially affects the lungs of patients, X-ray imaging of the chest is helpful for effective diagnosis. Any method for automatic, reliable, and accurate screening of COVID-19 infection would be beneficial for rapid detection and reducing medical or healthcare professional exposure to the virus. In the past, Convolutional Neural Networks (CNNs) proved to be quite successful in the classification of medical images. In this study, an automatic deep learning classification method for detecting COVID-19 from chest X-ray images is suggested using a CNN. A dataset consisting of 3616 COVID-19 chest X-ray images and 10,192 healthy chest X-ray images was used. The original data were then augmented to increase the data sample to 26,000 COVID-19 and 26,000 healthy X-ray images. The dataset was enhanced using histogram equalization, spectrum, grays, cyan and normalized with NCLAHE before being applied to CNN models. Initially using the dataset, the symptoms of COVID-19 were detected by employing eleven existing CNN models; VGG16, VGG19, MobileNetV2, InceptionV3, NFNet, ResNet50, ResNet101, DenseNet, EfficientNetB7, AlexNet, and GoogLeNet. From the models, MobileNetV2 was selected for further modification to obtain a higher accuracy of COVID-19 detection. Performance evaluation of the models was demonstrated using a confusion matrix. It was observed that the modified MobileNetV2 model proposed in the study gave the highest accuracy of 98% in classifying COVID-19 and healthy chest X-rays among all the implemented CNN models. The second-best performance was achieved from the pre-trained MobileNetV2 with an accuracy of 97%, followed by VGG19 and ResNet101 with 95% accuracy for both the models. The study compares the compilation time of the models. The proposed model required the least compilation time with 2 h, 50 min and 21 s. Finally, the Wilcoxon signed-rank test was performed to test the statistical significance. The results suggest that the proposed method can efficiently identify the symptoms of infection from chest X-ray images better than existing methods.

In recent years, the area of Medicine and Healthcare has made significant advances with the assistance of computational technology. During this time, new diagnostic techniques were developed. Cancer is the world's second-largest cause of mortality, claiming the lives of one out of every six individuals. The colon cancer variation is the most frequent and lethal of the numerous kinds of cancer. Identifying the illness at an early stage, on the other hand, substantially increases the odds of survival. A cancer diagnosis may be automated by using the power of Artificial Intelligence (AI), allowing us to evaluate more cases in less time and at a lower cost. In this research, CNN models are employed to analyse imaging data of colon cells. For colon cell image classification, CNN with max pooling and average pooling layers and MobileNetV2 models are utilized. To determine the learning rate, the models are trained and evaluated at various Epochs. It's found that the accuracy of the max pooling and average pooling layers is 97.49% and 95.48%, respectively. And MobileNetV2 outperforms the other two models with the most remarkable accuracy of 99.67% with a data loss rate of 1.24.

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In recent years, lung disease has increased manyfold, causing millions of casualties annually. To combat the crisis, an efficient, reliable, and affordable lung disease diagnosis technique has become indispensable. In this study, a multiclass classification of lung disease from frontal chest X-ray imaging using a fine-tuned CNN model is proposed. The classification is conducted on 10 disease classes of the lungs, namely COVID-19, Effusion, Tuberculosis, Pneumonia, Lung Opacity, Mass, Nodule, Pneumothorax, and Pulmonary Fibrosis, along with the Normal class. The dataset is a collective dataset gathered from multiple sources. After pre-processing and balancing the dataset with eight augmentation techniques, a total of 80,000 X-ray images were fed to the model for classification purposes. Initially, eight pre-trained CNN models, AlexNet, GoogLeNet, InceptionV3, MobileNetV2, VGG16, ResNet 50, DenseNet121, and EfficientNetB7, were employed on the dataset. Among these, the VGG16 achieved the highest accuracy at 92.95%. To further improve the classification accuracy, LungNet22 was constructed upon the primary structure of the VGG16 model. An ablation study was used in the work to determine the different hyper-parameters. Using the Adam Optimizer, the proposed model achieved a commendable accuracy of 98.89%. To verify the performance of the model, several performance matrices, including the ROC curve and the AUC values, were computed as well.

Alzheimer's disease is largely the underlying cause of dementia due to its progressive neurodegenerative nature among the elderly. The disease can be divided into five stages: Subjective Memory Concern (SMC), Mild Cognitive Impairment (MCI), Early MCI (EMCI), Late MCI (LMCI), and Alzheimer's Disease (AD). Alzheimer's disease is conventionally diagnosed using an MRI scan of the brain. In this research, we propose a fine-tuned convolutional neural network (CNN) classifier called AlzheimerNet, which can identify all five stages of Alzheimer's disease and the Normal Control (NC) class. The ADNI database's MRI scan dataset is obtained for use in training and testing the proposed model. To prepare the raw data for analysis, we applied the CLAHE image enhancement method. Data augmentation was used to remedy the unbalanced nature of the dataset and the resultant dataset consisted of 60000 image data on the 6 classes. Initially, five existing models including VGG16, MobileNetV2, AlexNet, ResNet50 and InceptionV3 were trained and tested to achieve test accuracies of 78.84%, 86.85%, 78.87%, 80.98% and 96.31% respectively. Since InceptionV3 provides the highest accuracy, this model is later modified to design the AlzheimerNet using RMSprop optimizer and learning rate 0.00001 to achieve the highest test accuracy of 98.67%. The five pre-trained models and the proposed fine-tuned model were compared in terms of various performance matrices to demonstrate whether the AlzheimerNet model is in fact performing better in classifying and detecting the six classes. An ablation study shows the hyperparameters used in the experiment. The suggested model outperforms the traditional methods for classifying Alzheimer's disease stages from brain MRI, as measured by a two-tailed Wilcoxon signed-rank test, with a significance of < 0.05.

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The pandemic has taken the world by storm. Almost the entire world went into lockdown to save the people from the deadly COVID-19. Scientists around the around have come up with several vaccines for the virus. Amongthem, Pfizer, Moderna, and AstraZeneca have become quite famous. General people however have been expressing their feelings about the safety and effectiveness of the vaccines on social media like Twitter. In this study, such tweets are being extracted from Twitter using a Twitter API authentication token. The raw tweets are stored and processed using NLP. The processed data is then classified using a supervised KNN classification algorithm. The algorithm classifies the data into three classes, positive, negative, and neutral. These classes refer to the sentiment of the general people whose Tweets are extracted for analysis. From the analysis it is seen that Pfizer shows 47.29%positive, 37.5% negative and 15.21% neutral, Moderna shows 46.16%positive, 40.71% negative, and 13.13% neutral, AstraZeneca shows 40.08%positive, 40.06% negative and 13.86% neutral sentiment.