Outbreaks of acute haemorrhagic conjunctivitis (AHC) - a rapidly progressing and highly contagious infection - often occur in schools during summer and autumn. We used dynamic modelling to evaluate the efficacy of interventions to control AHC outbreaks in schools. A susceptible-infected-recovered (SIR) model was built to simulate AHC outbreaks in Chinese schools, with isolation or school closure added into the model. We used outbreak data from the period 2004-2015 in our models to estimate the effective reproduction number and assess the efficacy of interventions. The median effective reproduction number (uncontrolled) of AHC outbreaks was 7·00 (range 1·77-25·87). The median effective reproduction number (controlled) of AHC outbreaks was 0·16 (range 0·00-2·28). Intervention efficacy is affected by the timing of isolation; earlier isolation is associated with a lower morbidity peak and smaller total attack rate (TAR). School closures were not effective; TARs were almost 100% and did not change even when different school closure durations were adopted. Isolation and school closure as a combined intervention strategy was used to simulate outbreak control, but the efficacy was the same as isolation alone. An isolation programme could be an effective primary intervention during AHC outbreaks in schools. However, school closure is not recommended.
In this paper, Pro/E software is used building an accurate parameterized cylindrical helical gear model, which is an accurate analysis model for ANSYS finite element analysis. The finite element calculation is conducted by use of the software ANSYS, analyzing the position of the most unfavorable load line of involute helical gear engagement as well as applying load on gear in virtue of the most unfavorable load line, increasing the accuracy of analysis and calculation of gear strength, and offering more accurate data for gear design. At the meantime, the effect of different fillets on the maximum root stress is studied, providing a quantitative basis for the case hardening method that enhances the bending strength of gear.
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