Scanning microscopy by itself cannot elucidate the mechanism of herpetic infection of the cornea, but it contributes to the study of the viral propagation on the corneal surface in experimental herpetic keratitis. The theory that the propagation takes place by the intermediary of the subepithelial nerve fibres seems to be the most probable. A localised disappearance of microvilli and the fusion of some of them to form tuberous formations were observed. The epithelial cells were detached from one another to form punctate, linear and dendritic lesions. Furthermore, by reproducing the essential changes of intracellular herpetic infection in situ, the recent primo-cultures of the corneal epithelium constitute a very valuable experimental model.
On the occasion of the observation of 4 cases of melanocytoma of the optic disc, the authors stress the relative rarity of this pigmented tumor, its benignity and its frequent association with a choroidal nevus. The melanocytoma is mostly stationary and produces no functional symptoms. It is generally diagnosed after the age of 30, and its pathogenesis is unknown.
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