Three male patients with severe osteoporosis were treated with human growth hormone. One of them had a primary osteoporosis, the two others osteogenesis imperfecta. The duration of therapy was 8 to 15 months and average doses per day were 1.45 to 2.3 mg. While clinical and 47calcium kinetic data failed to prove marked influences of the treatment, histomorphometry of bone biopsies showed indisputable changes. There was an increase of periosteal new bone formation as well as of intracortical bone resorption, while at the same time the relative activity of osteoblasts on endosteal surfaces showed a significant increase.

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The mineral content of the radius and the ulna was measured in 773 persons using 125J photon absorptiometry. Statistical evaluation of the data has provided normal values of mineral content of the forearm bones in men and women between the ages of 15 and 90 years. The course of the mineral content curve is discussed in relation to age and sex.

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Auf Grund seiner ausgedehnten pathologisch-anatomischen Studien als Chirurg an ,,lebenswarm fixierten Resektionspräparaten" vertrat besonders Konjetzny (1-9) die Auffassung, daß der Magenkrebs sich nicht in einer normalen Sdileimhaut entwickelt, sondern gewöhnlich auf dem Boden einer chronischen Schleimhautentzündung entsteht. Diese wurde als atrophisthe, hyperpiastische oder als atrophisth-hyperplastisdie Gastritis beschrieben. Dabei ist die Magenkrebsentwicklung weniger unter dem Gesichtspunkt der chro-2 Das Krankengut entstammt größtenteils der jahrelangen Zusammenarbeit zwischen Herrn Prof. Dr. Konjetzny (ehem. Direktor der Chirurgisthen KLinik

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Using 125I-photon absorption, skeletal mineral content was measured in 57 diabetics requiring insulin. Average age was 33 years, mean duration of diabetes 19 years. Abnormally reduced mineral content was detected in ten of 21 males and 11 of 36 women. This finding is interpreted as being a late complication of diabetes. Pathological fractures were not seen and there were very few complaints referable to the skeletal system.