We have developed the RIKEN Ajax Browser Computing (RABC) system. This system enables the simple realization of large scale Global Computing systems,like the SETI@home project, that take advantage of unused computing resources. Its greatest advantage is that an agent program, which has been traditionally required, does not need to be installed. Volunteers can participate by simply browsing to a webpage provided by the RABC system. This system allows greater CPU cycle resources to be acquired than traditional methods. We have evaluated a performance difference between JavaScript and legacy computer languages.
Academic publications have been evaluated with the impact on research communities based on the number of citations. On the other hand, the impact of academic publications on industry has been rarely studied. This paper investigates how academic publications contribute to software development by analyzing publication citations in source code comments in open source software repositories. We propose an automated approach of detecting academic publications based on Named Entity Recognition, and achieve 0.90 in F1 as detection accuracy. We conduct a large-scale study of publication citations with 319,438,977 comments collected from active 25,925 repositories written in seven programming languages. Our findings indicate that academic publications can be knowledge sources of software development, and there can be potential issues of obsoleting knowledge.
AimHepatitis C complicated by diabetes mellitus (DM) is considered a risk factor for the progression of fibrosis and development of hepatocellular carcinoma (HCC) and cardiovascular diseases. However, several studies may have lacked appropriate diagnosis of glucose intolerance. We aimed to examine the risk associated with abnormal glucose intolerance in the development of liver‐related diseases, including HCC and complications of liver cirrhosis, such as ascites, esophageal and gastric varices, and hepatic encephalopathy, and cardiovascular diseases in patients with hepatitis C accurately diagnosed with impaired glucose tolerance.MethodsThis longitudinal retrospective study included 365 patients with chronic hepatitis C admitted to Ehime University Hospital for anti‐hepatitis C therapy between September 1991 and January 2015. Patients were classified into normal glucose tolerance (NGT), prediabetes, and DM groups based on 75‐g oral glucose tolerance test results.ResultsBoth univariate and multivariate (adjusted for potential confounders) analyses revealed a significantly higher risk of developing HCC and cardiovascular events in the DM group than in the NGT group. However, in multivariate analysis, liver‐related events, particularly liver cirrhosis complications, revealed no significant association. In addition, the prediabetes group had no significant risk of any outcome.ConclusionsPatients with hepatitis C complicated by DM, compared with patients with hepatitis C with NGT or complicated with prediabetes, have a higher risk of HCC and cardiovascular disease events, but not liver‐related events, particularly in not developing liver cirrhosis complications. Therefore, appropriate follow‐up is required for patients with hepatitis C based on their glucose tolerance status.
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