An accurate understanding of the factors that influence farmers' adoption of a crop is critical for effective policy promotion and technical support. Agroforestry crop adoption is a complex topic involving many factors not often addressed by tradition crop adoption models. This complexity, when applied to Jatropha (Jatropha curcas L.), an often widely promoted yet poorly understood biofuel feedstock crop, requires a detailed analysis across diverse topics. Such an analysis was carried out through applying rigorous statistical tools to the data acquired from an interview-based household survey among Malian farmers and was combined with relevant geospatial datasets. The results showed that though farmers' adoption is based on a wide variety of factors from household preferences, resource endowments, bio-physical factors, and market incentives, factors related to risk and uncertainty appear to provide the strongest correlation. Specifically, the number of visits that an agriculture extension agent makes with a farmer was found to be the most significant factor influencing adoption.