The presence and amount of histologic lipid in many adrenal adenomas accounts for their low attenuation on unenhanced CT scans and their loss in relative signal intensity on chemical shift MR images.
CT densitometry on delayed scans obtained 1 hour after contrast enhancement may be useful in characterizing an adrenal mass as an adenoma. When CT is performed with a 150-mL bolus injection of contrast material and with the scanning parameters described in this study, other procedures or imaging studies may be unnecessary if the mass measures less than 30 HU on the delayed scans.
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