cluding the liver, spleen, sinuses, and the diploic spaces of the skull. Oral health problems in patients with thalassemias are mostly related to a varied degree of facial deformities, malocclusions, and/or dental arch dimensions. We present a case with a 69-year-old man, diagnosed with homozygous α thalassemia that came to the Faculty of Dentistry at the University of Murcia for a dental treatment. His medical history was notable for recurrent episodes of bleeding since childhood. Panoramic radiography revealed changes in the mandible, with widening of medullary spaces, coarsening of the trabeculae and thinning of cortical bone because of a compensatory extramedullary hematopoiesis Here, a brief review of the clinical, radiographic, laboratory, and dental implications of these hemoglobin disorders are presented. The patient required several dental extractions and two blood transfusions were administered the same day of the intervention. Thereafter, additional transfusions were planned only depending on the degree of bleeding.
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