In this article, we consider cancer tumor models and investigate the need for fractional order derivative as compared to the classical first order derivative in time. Three different cases of the net killing rate are taken into account including the case where net killing rate of the cancer cells is dependent on the concentration of the cells. At first, we use a relatively new analytical technique called q-Homotopy Analysis Method on the resulting time-fractional partial differential equations to obtain analytical solution in form of convergent series with easily computable components. Our numerical analysis enables us to give some recommendations on the appropriate order (fractional) of derivative in time to be used in modeling cancer tumor. C 2014 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License.
In a recent work [1,2] Sjöberg remarked that generalization of the double reduction theory to partial differential equations of higher dimensions is still an open problem. In this note we have attempted to provide this generalization to find invariant solution for a non linear system of qth order partial differential equations with n independent and m dependent variables provided that the non linear system of partial differential equations admits a nontrivial conserved form which has at least one associated symmetry in every reduction. In order to give an application of the procedure we apply it to the nonlinear (2 + 1) wave equation for arbitrary function f (u) and g (u).
Symmetries of spacetime manifolds which are given by Killing vectors are compared with the symmetries of the Lagrangians of the respective spacetimes. We find the point generators of the one parameter Lie groups of transformations that leave invariant the action integral corresponding to the Lagrangian (Noether symmetries). In the examples considered, it is shown that the Noether symmetries obtained by considering the Larangians provide additional symmetries which are not provided by the Killing vectors. It is conjectured that these symmetries would always provide a larger Lie algebra of which the KV symmetres will form a subalgebra.
The complete symmetry group classification of the fourth-order Euler–Bernoulli ordinary differential equation, where the elastic modulus and the area moment of inertia are constants and the applied load is a function of the normal displacement, is obtained. We perform the Lie and Noether symmetry analysis of this problem. In the Lie analysis, the principal Lie algebra which is one dimensional extends in four cases, viz. the linear, exponential, general power law, and a negative fractional power law. It is further shown that two cases arise in the Noether classification with respect to the standard Lagrangian. That is, the linear case for which the Noether algebra dimension is one less than the Lie algebra dimension as well as the negative fractional power law. In the latter case the Noether algebra is three dimensional and is isomorphic to the Lie algebra which is sl(2,R). This exceptional case, although admitting the nonsolvable algebra sl(2,R), remarkably allows for a two-parameter family of exact solutions via the Noether integrals. The Lie reduction gives a second-order ordinary differential equation which has nonlocal symmetry.
A similarity analysis of a nonlinear fin equation has been carried out by M. Pakdemirli and A.Z. Sahin [Similarity analysis of a nonlinear fin equation, Appl. Math. Lett. (2005) (in press)]. Here, we consider a further group theoretic analysis that leads to an alternative set of exact solutions or reduced equations with an emphasis on travelling wave solutions, steady state type solutions and solutions not appearing elsewhere.
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