Short-term turmeric supplementation can attenuate proteinuria, TGF-β and IL-8 in patients with overt type 2 diabetic nephropathy and can be administered as a safe adjuvant therapy for these patients.

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The present study was conducted to investigate the prevalence of Eimeria species in native chickens reared under semi-scavenging system and were allowed to scavenge in the yard, in crop fields near water reservoirs. We studied 200 scavenging native chickens in villages around Shiraz City in Southwest Iran. These chickens had no history of vaccination against coccidiosis and had never been given coccidiostat drugs. The chickens were submitted for post-mortem and parasitological examinations. All the villages had chickens that were positive for different Eimeria spp. From a total of 200 native chickens examined, 128 (64%) were infected with coccidiosis. Eimeria tenella was the most prevalent species (24%) followed by Eimeria acervulina (18%), Eimeria necatrix (12%), and Eimeria maxima (10%). Prevalences varied by management and did not vary by flock size.

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Background. In several published research, the evaluation of renal disorders using immunofluorescence on formalin-fixed, paraffin-embedded (FFPE) tissue sections versus immunofluorescence on frozen sections was compared. Each technique’s accuracy varies greatly. This study’s objective was to assess IF-P as a potential replacement for IF-F in the diagnosis of renal biopsy specimens. Materials and Methods. To show immunoglobulin IgA, IgG, IgM, and C3 immune deposits, proteinase K digestion of paraffin-embedded renal biopsy was standardized and used in 51 renal biopsies. Sensitivity, specificity, false-positive, and false-negative values were calculated. Results. IF-P showed a sensitivity of 93.1%, 76.9%, 63.6%, and 33.3%, and a specificity of 100%, 97.3%, 95%, and 100% for IgG, IgA, IgM, and C3, respectively. Compared to cases that had both routine IF and IF-P, 50 of 51 showed either the same amount of staining for the diagnostic immunoglobulin/complement or a small amount of difference. In most of the cases (49 of 51), diagnostic findings were found. Conclusion. IF-P is a sensitive and precise approach for assessing immune deposits in renal tissue biopsies. We come to the conclusion that IF-P serves as a beneficial salvage immunohistochemistry method for renal biopsies that do not contain enough cortical tissue for IF-F.