BACK GROUND:Cutaneous appendageal tumours are a large diverse group of tumours that are commonly classified according to their state of appendageal differentiationeccrine, apocrine, follicular and sebaceous. MATERIALS AND METHODS: This is a retrospective study that reviewed the clinical records of patients from the Department of pathology, Govt Kilpauk medical college who were diagnosed with skin tumours by histopathology for a period of three years. Afterwards, these cases were, reviewed diagnoses were recorded and classified and analysed according to the patient's age, gender, and localization, occupation, exposure to sunlight and clinical presentation. RESULTS: This descriptive study was an analysis of 29 adnexal tumors with regard to age, clinical presentation, occupation and its correlation with histologic diagnosis. Benign tumors were common and composed of 74% and malignant tumors were 26%. . Mean age of presentation of adnexal tumors in this study was 35.2 years with female predominance. 15 of these tumours were derived from eccrine and apocrine glands, 11 of them showed follicular differentiation, and 3 of them showed sebaceous differentiation. They showed a maximum occurrence in face as nodular and papular lesions. Commonest lesion was Trichoepithelioma. CONCLUSION: Adnexal skin tumors have distinct histological patterns which differentiates them from other cutaneous tumors. Clinical diagnosis of adnexal tumors is extremely difficult because various adnexal tumors have similar clinical presentation and histopathological examination becomes essential in diagnosis
Background: The mediastinum is the space between the two lungs, bounded anteriorly by the sternum and posteriorly by the vertebral column. A spectrum of neoplastic and non-neoplastic lesions can arise in the mediastinum. Methods: A total of 14 cases were retrospectively retrieved from the Histopathology department. The cases had histopathological diagnosis either in image guided, thorocoscopic, transbronchial or excision biopsies. Results: The majority of cases (43% n=6) were of thymic origin, which included both neoplastic lesions of thymoma group and non-neoplastic lesion like thymic cysts. The thymoma group included 3 cases of thymoma B3 and 1 case of thymoma AB. The lymphoid lesions include Hodgkin lymphoma (14.3%; n=2) and non-Hodgkin lymphoma (7.1%; n=1). The mesenchymal lesions (21.4%; n=3) included lipoma, solitary fibrous tumor and schwannoma which accounts for one case each. A rare case of ectopic parathyroid adenoma (7.1%; n=1). and a case of metastatic papillary carcinoma (7.1%; n=1) were also reported. Conclusion: The diagnosis of mediastinal mass lesions can pose difficulties due to its wide clinicopathologic spectrum to the clinician, radiologists and pathologist. A multimodal approach with histopathological examination and immunohistochemistry can help in arriving at an accurate diagnosis.
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