In this retrospective study, we determined the incidence, serovars, and antibiogram of
Vibrio cholerae
isolated from 102 clinical stool samples collected from rice water diarrheic patients during an outbreak (May - July 2017) in Ilorin metropolis, Nigeria. The culture positive rate of the
V. cholerae
isolates was 41.2%, with 41 and 1 isolates from O1 (Inaba) and non-O1/O139 serogroups, respectively. The isolates were the most susceptible to ciprofloxacin (76.2%) followed by amoxicillin-clavulanate (71.4%). However, all isolates were resistant to ampicillin and tetracycline. In conclusion,
V. cholerae
O1 was the predominant circulating serogroup exhibiting multi-drug resistance during the outbreak.
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