Lymphadenopathy is a common clinical manifestation which requires rapid and accurate diagnosis. Fine Needle Aspiration Biopsy (FNAB) is used as an initial and direct diagnosis in cases of lymphadenopathy, confirmatory diagnosis of colli lymphadenopathy is carried out by histopathological examination. The purpose of this study was to determine the value of the FNAB diagnostic test for lymphadenopathy colli FNAB against the gold standard histopathology of Paraffin Blok for benign and malignant lymphadenopathy. This type of research is observational descriptive by taking medical record data (SIM-RS) of patients with lymphadenopathy in the colli region who were examined for FNAB and histopathology at the Anatomical Pathology Laboratory Installation, RSPAL dr. Ramelan Surabaya for the period January 2019 – March 2022. The sample used was selected using the total sampling method, obtained as many as 66 samples that met the inclusion criteria. The results of the FNAB examination were then matched against the histopathological gold standard examination data. Furthermore, the data was processed by 2x2 crosstabulation and diagnostic tests were carried out to determine the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy. The results showed that the accuracy of the FNAB diagnostic test was 86.56%, sensitivity 80.48%, specificity 96.15%, positive predictive value 97.05%, negative predictive value 75.75%. In general, it can be stated that the FNAB examination can be a screening diagnostic tool that is easy, fast, relatively affordable and applicable in helping to establish the diagnosis of colli lymphadenopathy.
Gastritis is an inflammatory disease that can last for a long time. Helicobacter pylori infection is known as the main cause of peptic ulcer and the most common cause of gastritis. Helicobacter Pylori infection will cause mononuclear (MN) and polymorphonuclear (PMN) cell infiltration and will increase the production of proinflammatory cytokines in the gastric mucosa compared to non-Helicobacter Pylori gastritis. Helicobacter Pylori with histopathological examination diagnosis. This type of research is descriptive observational with purposive sampling data collection technique at the Anatomical Pathology Laboratory Installation, RSPAL dr. Ramelan Surabaya. The data used are the results of a biopsy of 60 samples that were determined as gastritis with histopathological examination of the identification of Helicobacter Pylori bacteria in gastric tissue classified by the level of bacterial density using The Updated Sydney System, as well as haemogram data for complete blood examination to further calculate the neutrophil lymphocyte ratio (NLR). The data were processed using descriptive statistical tests to determine the average neutrophil lymphocyte ratio (NLR). Based on the statistics of the r-Spearman test, the density of Helicobacter Pylori, (Pν = 0.000) below < 0.005 indicates that there is a strong relationship between the neutrophil lymphocyte ratio (NLR) and the density of Helicobacter Pylori bacteria.
Background Smoking has become one of the leading causes of death worldwide. The negative impact of smoking usually occurs after a few years when a person starts actively smoking can harm the body's organs and become a major risk factor for diseases with inflammatory components. Systemic inflammatory reactions are characterized by an increase in inflammatory cytokines, blood cell counts and blood viscosity. Examination CRP and ESR are the two most frequently measured laboratory tests in assessing the response of a systemic inflammatory process. This study aims to determine and analyze the correlation between ESR values and hs-CRP in active smokers at coffee shops, East Surabaya.
Methods: The type of research used is correlation research with cross sectional. The sample used is 30 active smokers who meet the inclusion criteria. This research was carried out on February 21 – April 11, 2022. The examination of ESR values and hs-CRP levels was carried out at Balai Besar Laboratorium Kesehatan (BBLK) Surabaya.
Results: It was found that 30 respondents had been actively smoking >5 years with a percentage of 100%. as many as 8 respondents consumed 1-10 cigarettes/day with a percentage of 27%, 19 respondents consumed 10-20 cigarettes per/with a percentage of 63%, and 3 respondents consumed >20 cigarettes/day with a percentage of 10%. The average value of ESR is 8.37 mm/Hr and The The average value of the of hs-CRP 1.11 mg/L.
Conclusion: Based on statistical tests, There is no correlation between the value of ESR and hs-CRP in active smokers in a coffee shop in the East Surabaya area (p value = 0.099) with a sufficient relationship and a positive direction of relationship (r = 0.307).
Chronic kidney failure is caused by the body's inability to maintain metabolism and fluid balance due to progressive kidney function disorders that will trigger anemia. The cause of anemia in kidney failure is inflammation, which causes inhibition of iron release, resulting in a decrease in iron in the body. Signs of iron deficiency in chronic kidney failure are low levels of Total Iron Binding Capacity (TIBC) and in complete blood count; there is an increase in levels of Red Cell Distribution Width (RDW). This study aims to determine the relationship between Red Cell Distribution Width (RDW) and the results of Total Iron Binding Capacity (TIBC) in patients with chronic kidney failure with anemia. This study was conducted in January-April 2022, using a cross sectional method on 30 samples of patients with chronic kidney failure with anemia by examining a sample of patients at the Haji Regional General Hospital Surabaya. Most of the research results of the research subjects were male (n =16; 53,3%). The normal RDW is 33,3% (10/30), the high RDW is 66,7% (20/30), the low TIBC is 76,7% (23/30), and the normal TIBC is 23,3% (7/30). As much as 53,3% (16/30) for high RDW values with low TIBC. The result of the Pearson correlation test between RDW and TIBC was r = 0.014 (p = 0.940). Therefore, there is no significant relationship between RDW and TIBC in CKD patients with anemia at the Haji Surabaya Hospital.
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