C2 lamina anatomy generally permitted screw fixation in most studies, but there was disagreement about risk of vertebral artery injury. Preoperative computed tomography was generally recommended, while, according to some authors, three-dimensional reconstruction could be essential. However, there is a relative lack of studies about non-Asian populations. More research could further illustrate the anatomy of C2 lamina, clarify the safety of axis fixation for more populations and perhaps modify preoperative imaging protocols.
<p>PDF file - 100K, Supplementary Methods including: cells, antibodies, preparation of GST-eIF4E and GB1-eIF4E proteins, assessing protein/compound binding by saturation transfer difference (STD) and 1D 1H-NMR spectra, assessing protein/compound binding with protein titration and 1D 1H-NMR spectra, fluorescence intensity quenching, pharmacokinetic analysis and routes of ON 013105 administration.</p>
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