International audienceCow’s milk contains bioactive secondary phenolic compounds that are formed by bovine’s gut bacterial flora from plant phenolic compounds. Equol, a metabolite of daidzein, is one such secondary compounds of biological interest. The potential of phenolic compounds in milk as dietary antioxidants and their distribution within the milk matrix were examined. The equol concentrations, total phenolic contents, and antioxidant activity (Trolox equivalent antioxidant capacity and inhibition of F2-isoprostanes formation by human neutrophils in vitro) were measured and compared in commercial cow’s milk of varying lipid contents. The Trolox equivalent antioxidant capacity and ability to inhibit F2-isoprostanes formation in vitro increased with the concentrations of phenolic compounds and equol in the milk. Equol and total phenolic compound concentrations correlated positively with the milk lipid concentrations. Separate experiments using homogenized and non-homogenized milk showed that dairy equol and phenolic compounds distributed to larger extent in the lipid fraction than in the aqueous fraction of cow’s milk. Our results showed that cow’s milk may serve as a dietary source of unique phenolic compounds, such as equol. Skimming of cow’s milk may reduce the original amount of equol and phenolic compounds and thereby diminishes the overall nutritive value and functional properties of cow’s milk
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.