The purpose of this study was to examine the effectiveness of a therapeutic community program on resilience and positive change of lifestyle in people with alcohol use disorder. This study used a quasi-experimental study design. The Therapeutic Community Program was conducted daily for 12 weeks from June 2017 to May 2018. Subjects were selected from the Therapeutic Community and a hospital. Of the 38 subjects, 19 subjects belonged to the experimental group and 19 subjects belonged to the control group. Our findings were that the Therapeutic Community Program has improved resilience and promoted global lifestyle changes in the experimental group compared with the control group.