We found that doses of 100 Gy (110 microCi/g), 200 Gy (220 microCi/g), and 300 Gy (330 microCi/g) resulted in hypothyroidism in 50%, 70%, and 95% of treated individuals, respectively. These data show that to insure ablation of thyroid tissue doses, >270 Gy (300 microCi/g) is needed, especially when the thyroid is large.
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