A review of current literature on mammalian hosts' sexual dimorphism (SD) in parasitic infections revealed that (1) it is a scarcely and superficially studied biological phenomenon of considerable significance for individual health, behavior, and lifestyles and for the evolution of species; (2) there are many notable exceptions to the rule of a favorable female bias in susceptibility to infection; (3) a complex network of molecular and cellular reactions connecting the host's immuno-neuroendocrine systems with those of the parasite is responsible for the host-parasite relationship rather than just an adaptive immune response and sex hormones; (4) a lack of gender-specific immune profiles in response to different infections; (5) the direct effects of the host hormones on parasite physiology may significantly contribute to SD in parasitism; and (6) the need to enrich the reductionist approach to complex biological issues, like SD, with more penetrating approaches to the study of cause-effect relationships, i.e., network theory. The review concludes by advising against generalization regarding SD and parasitism and by pointing to some of the most promising lines of research.
Sex differences in immune function are relatively well studied in vertebrate animals, although the patterns are not always clear in birds. The study of immune responses in nestlings of wild bird populations may constitute an appropriate way to investigate inherent intersexual differences while controlling for environmental conditions such as parasitism that affect male and female individuals growing in the same nest. We studied whether the cell-mediated immune response, as measured by phytohaemagglutinin (PHA) injection, and the levels of circulating antibodies differ between sexes of Pied Flycatcher nestlings Ficedula hypoleuca. No sex differences in nestling cell-mediated immune response were found, but females showed significantly higher levels of plasma immunoglobulins than males did. Although nestling birds may not have a fully functional humoral immune defence, our study indicates that sex differences in the humoral component exist at this early stage of life. Given the importance of antibodies in the fight against parasite, bacterial and viral infections, the intrinsic sex disparity in circulating antibodies may have important implications for the life history of each sex.
The use of inexpensive benchtop plotters in combination with refillable writing pens and markers as a powerful route to print nanomaterial‐based inks on paper substrates is studied. It is proved that this approach is very robust, it can be used to print inks of many different solution‐processable nanomaterials, and is very precise, allowing pattern features with pitch separation as narrow as 80 μm. The general character of this printing platform by printing van der Waals materials, organic semiconductors, hybrid perovskites and colloidal nanoparticles with a broad range of properties (from insulators to superconductors) is illustrated. The system is used to easily create several example applications such as an all‐printed, paper‐supported photodetector. This printing platform can be very helpful for research groups with a wealth of expertise in synthesis of solution‐processable nanomaterials but that lack the infrastructure, resources, and expertise to perform traditional inkjet printing for fast device prototyping.
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