The present study deals with the effect of one of the traditionally used Ethiopian medicinal plants, Bersama abyssinica, on gut motility. The experiment was carried out on isolated guinea-pig ileum with a standard spasmogen, histamine, in the absence and presence of the water extract of the medicinal plant. The spasmogenic effect of histamine was found to be antagonized by the extract in a nonreversible manner, indicating that B . abyssinica has a spasmolytic activity.
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