Ahnormal .;c.cr-ctions have 1,cc.n I-ccogni/ctl lbr-some time :IS orlc ol' the h;isic al,nor-rn;rlitics i l l ~~:rticnts with ('I' ( 1 , 2). li)rcxaml,lc the elevation ol'\otlium Icvcls in seer-ctioris is a consistent Iintlir~g iri ('1. (3).Salivi~r-y glarrds seer-ctc a n isotonic solution ol'clcct~-olytcs and m:icr-omolcc.rrlc.;, but during its Ixrssagc tlrrougli the glantlul:rr ducts ions arc rcahsor-llctl and thc solution I~ccorlics Iiypo(onic. 1):rnn and Iflatr (4) suggested in 107X that the rcahsor-plion 01' ions in glantluli~r ducts is contr-ollctl by :(I-gininc cstci-ascs which arc ~,r.cscrrl in the 1:l;rntls. At the w m c lime thcy ~,r-ol,osctl th:rt abnormal clcctr-olvtc conccrltr-ations in ('1: sccr-ctions arc c:r~rscd by a tlclicicncy ill cithc*r-tlic glandular-hallikrcin, whicll itsc~lI'li:rs 21-gi nine ester-asc activity, or-in sorric otlicr-ar-gininc cstcrasc. In 108 I
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