SummaryBackground/Aim: Dental care settings invariably carry the risk of Coronavirus Disease 2019 (COVID-19) infection because dental practice involves face-to-face communication with patients and the generation of large amounts of aerosol and droplets mixed with patients’ saliva. Since droplet and aerosol transmission are the most important concerns in dental clinics, informing future dentists about pandemic diseases at the undergraduate stage is important. In this context, the aim of this study was to compare the knowledge and attitudes of clinical and preclinical dental students regarding the COVID-19 pandemic.Material and Methods: 159 preclinical and 130 clinical dental students were included in this cross sectional study. The researchers developed a closed-ended questionnaire with the help of the existing literature. The questionnaire contained 17 questions about the knowledge and attitudes of dental students regarding the COVID-19 pandemic.Results: Clinical students feel significantly more threatened with exposure to COVID-19 infection than preclinical students (p<0.05, chi-square test). The proportion of students who do not want to treat an individual who has had a COVID-19 infection and recovered is statistically higher in clinical students (p<0.05, chi-square test). The proportion of students who think that using protective equipment during dental practice will not protect them against COVID-19 infection is statistically higher in clinical students (p<0.05, chi-square test).Conclusions: More education and training courses are need in order to improve students’ knowledge and attitudes regarding newly emerging pandemic diseases.
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multifunctional cytokine that regulates inflammatory responses in various autoimmune and inflammatory disorders. Objective: The purpose of this study was to analyze the gingival crevicular fluid (GCF) for GM-CSF, interleukin-1 beta (IL-1β), and macrophage inflammatory protein-1 alpha (MIP-1α) levels in patients with stage I, stage II, stage III, and stage IV periodontitis (SI-P, SII-P, SIII-P, and SIV-P). Methodology: A total of 126 individuals were recruited for this study, including 21 periodontal healthy (PH), 21 gingivitis (G), 21 SI-P, 21 SII-P, 21 SIII-P, and 21 SIV-P patients. Plaque index (PI), gingival index (GI), presence of bleeding on probing (BOP), probing depth (PD), and attachment loss (AL) were used during the clinical periodontal assessment. GCF samples were obtained and analyzed by an enzyme-linked immunosorbent assay (ELISA). Results: GCF GM-CSF, MIP-1α, and IL-1β were significantly higher in SII-P and SIII-P groups than in PH, G, and SI-P groups (p<0.05). There was no significant difference among the PH, G, and SI-P groups in IL-1β, GM-CSF, and MIP-1α levels (p>0.05). Conclusions: These results show that GM-CSF expression was increased in SII-P, SIII-P, and SIV-P. Furthermore, GM-CSF levels may have some potential to discriminate between early and advanced stages of periodontitis.
Objectives: Classification systems of periodontitis have changed several times over the past 30 years as new information gathered about the pathophysiology of the disease rendered previous systems inadequate for classifying the diagnoses of all patients. Although the 1999 classification system was widely used in clinical practice and scientific studies, it had significant limitations leading to the reclassification introduced in 2017. In this context, the aim of this study is to evaluate how individuals diagnosed with periodontitis under the 1999 system were reclassified according to the 2017 system. Materials and Methods:Participants diagnosed with periodontitis according to 1999 classification and who had not received periodontal treatment in the last six months were included in the study. The patient assessment procedure consisted of a comprehensive periodontal diagnosis through periodontal charting and full-mouth radiography.Results: A total of 315 subjects (133 males and 182 females) were included in the study. According to the new classifications, 42 patients (17.94%) previously diagnosed with generalized chronic periodontitis according to 1999 classifications, were now classified as healthy with reduced periodontium, and 11 (4.7%) patients were classified as gingival inflammation with reduced periodontium. 63 (26.92%) patients were classified as SIII-GC and 33 patients (14.14%) as SIV-GC. Conclusions:The new classification system is based on not only disease severity but also the dimensions of an individual's disease which include complexity and risk factors.
Background: At the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions, periodontitis was reclassified according to a multidimensional staging and grading system. Grading takes variabilities in the rate of disease progression into account, relying on recognized progression risk factors, and is based on the assessment of bone loss at the worst-affected tooth in the dentition as a function of age, which is then modified by factors such as smoking and diabetes mellitus. In this context, the aim of this study was to determine whether there are correlations between radiographically calculated grades and grades modified by the presence of smoking or diabetes. Materials and Methods: In this descriptive study, individuals diagnosed with periodontitis according to the 2017 classifications were examined. The grade of periodontitis was measured using periapical radiography. A modified-grade level was assigned to the patients according to their glycated hemoglobin levels (in diabetics) or their smoking status. Results: The study included 341 individuals. No statistically significant relationship was revealed by Chi-square testing ( P > 0.05) or in the kappa agreement index between the modified grades and the radiographic grades. Conclusions: Although there was no correlation between radiographic grade and modified grade in smokers and diabetic individuals, increasing the grade score in these individuals in accordance with the 2017 classification provides clinicians the opportunity to develop a risk-based treatment plan, commensurate with the severity of periodontal disease and the level of risk.
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