The absolute or relative percentage washout of contrast material on delayed contrast-enhanced CT is a highly specific test for the differentiation of lipid-poor and lipid-rich adrenal adenomas from adrenal nonadenomas.
Cite as: Can Urol Assoc J 2014;8(1-2):e54-6. http://dx.doi.org/10.5489/cuaj.1242 Published online January 14, 2014. AbstractPrimary malignant melanoma of the bladder is very rare. Rather than being a primary lesion, malignant melanomas of the bladder are more commonly metastatic lesions. The histopathological appearance largely does not differ from that of melanoma at other body sites. It is often difficult to discriminate whether a bladder melanoma is primary or metastatic. Therefore, a careful review of histological features and performing necessary immunohistochemical staining procedures for S-100 protein and HMB-45 are very important in achieving a correct diagnosis. We report a case of hypomelanotic malignant melanoma of the bladder. Despite the variety of therapies available for primary melanomas of the bladder, the prognosis is still poor.
Neurofibromatosis or von Recklinghausen's disease is the most common inherited syndrome predisposing to neoplasia. Carcinosarcoma is a rare malignant mixed tumor of the lung. Association of carcinosarcoma of lung with Neurofibromatosis-1 is not common. A 57-year-old man presented with history of fever, cough, hemoptysis, breathlessness, weight loss, chest pain. Multiple cutaneous neurofibromas and café au lait spots were revealed by physical examination. A homogeneous opacity was found in the right middle and right upper zone on posterior-anterior chest radiography. A 8x8x7 cm mass that had irregular borders in right upper posterior and apical segment was seen on contrast enhanced chest computed tomography. On bronchoscopy, the lumen of right upper apical segment was obstructed with vegetating tumoral lesion. The biopsy taken from this region was diagnosed as carcinosarcoma by histopathological and immunohistochemical examination.A rare case with carcinosarcoma of the lung and Neurofibromatosis-1 was reported.
Adrenal myelolipoma is a rare benign tumour. This tumour is generally considered as a type of hormonally inactive neoplasm, which is composed of mature adipose tissue and normal haematopoietic cells. Rarely adrenal myelolipoma and adrenal cortical adenoma could be found together in the same gland. Due to myelolipoma's asymptomatic character, it is generally diagnosed incidentally. In fact, myelolipoma can now be easily detected because of improved techniques such as ultrasound, CT and MRI and widespread use of imaging. Because of this a 66-year-old male patient with abdominal pain, proved that adrenal myelolipoma and non-functional adrenal cortical adenoma are rare in the same gland. The case presented here deals with different outcome which is rare in the literature.
Inflammatory fibroid polyp (Vanek's tumor) is a rare benign polypoid lesion of the gastrointestinal tract. It often varies between 1-3 cm in diameter. It is usually seen in 60-70 years. Microscopically, proliferate spindle cells which localized around the vessels concentrically and eosinophil-rich inflammatory infiltrate are seen. In the differential diagnosis, many benign mesenchymal tumors of gastrointestinal tract, especially gastrointestinal stromal tumor, should be considered. 70 year old male patient, admitted with epigastric pain, nausea, fever after eating, had normal laboratory values except anemia. Contrast-enhanced computed tomography revealed a polypoid mass about 4 cm in diameter in the cardia and he was operated on suspicion of gastrointestinal stromal tumor. In the microscopic examination of excision material, numerous small and large vein structures, spindle cell proliferation and eosinophil-rich inflammatory infiltrate were observed. Immunohistochemically, CD117, CD34, smooth muscle actin, desmin, S-100, cytokeratin, DOG 1 were negative, Vimentin was strongly positive and Ki-67 proliferation index was 2%. The diagnose was "inflammatory fibroid polyp". The case is presented because of the unusually localization, large diameter, its rare occurrence and the potential risk of confusion with gastrointestinal stromal tumor.
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