OBJECTIVES: Vertebrobasilar insuffi ciency (VBI) is a pathology arising from the reduction in fl ow rate of vertebral arteries and mainly caused by infl ammation and atherosclerosis. Gamma-glutamyltransferase (GGT) is a marker which has been recently recognized as a marker of infl ammation and atherosclerosis. We aimed to investigate the relationship between GGT levels and VBI for the fi rst time. METHODS: In this cross-sectional study, of 3100 subjects who had vertebrobasilar doppler ultrasonography (VBU) were evaluated and 1042 of them who met the inclusion criterias were included. VBU reports, GGT levels, blood chemistry, lipid profi le were received from patients' fi les. Patients were evaluated according to VBU measurements and divided into two groups,VBI and non-VBI. RESULTS: Mean vertebral arterial blood fl ow volume values were 149.99±32.93 mL/m in VBI group and 286.88 ± 70.98 mL/m in non-VBI group. Mean GGT and CRP values were signifi cantly higher in the VBI group than in the non-VBY group (p < 0.001) ( p < 0.001), respectively. Vertebral artery blood fl ow volume was negatively correlated with GGT (r: -0.208, p < 0.001) and CRP (r: -0.119, p < 0.001). CONCLUSION: We demonstrated a signifi cant correlation between serum GGT levels and VBI. In addition, higher GGT level was an independent risk factor for the presence of vertebrobasilar system infl ammation and atherosclerosis (Tab. 2, Fig. 3, Ref. 27). Text in PDF www.elis.sk.
Objective: The aim of this study was to evaluate the organic voice disorders diagnosed by laryngostroboscopic examination and the distribution of the lesion types occording to age gender and the year in our otolaryngology department .Material and methods: Laryngostroboscopic records between October 2011-July 2014 were retrospectively analysed. The patients with organic voice desorders aged between 7-86 were included the study. The age, gender, the type of the lesion and the year of the examination were recorded. The types of the lesions were recorded, and the distribution of lesions according to gerder, age and the year were compared.Results: Total of 584 patients with organic pathology 41.8% were female, 52.2% were males. The distrubition of the lesions were 25.7% polyps, %17 reinke's edema and15.9 % nodules. The vocal cord nodules were seen in adult females and children. The male patiens had vocal polyps more frequent than females and the difference was statistically significant (%38.9, %18 respectively; p<0.05). The cysts were seen more in adult women than men and the difference was statistically significant (% 7.9, %3.3 respectively; p<0.05) The presbilarynx was found statistically significantly less frequently in adult women than men (%1, %5.3 respectively) (p<0.05). The incidence of laryngeal papillomatosis in adult men (2.5%) were statistically significantly more than women (p <0.05). The vocal cord nodules were found statistically significantly more frequently in patiens under 18 than adults (82.9%, %13.4; p<0.05).Conclusion: The laryngostroboscopic examination is important in decision of the treatment and the classifying of the cord vocal lesions. There are differences between the distribution of benign vocal cord lesions according to age, gender and the year of the examination.Key Words: Laryngostroboscopy, dysphonia, vocal cord Amaç: Kulak burun bo az poliklini imizde laringostroboskobik de erlendirme sonucunda tan konulan organik ses bozuklu una yol açan patolojilerin ya a, cinsiyete, y llara ve görülme s kl na göre da l mlar n n kar la t r lmas amaçlanm t r.Materyal metod: 2011 Haziran-2014 Temmuz tarihleri aras nda yap lan 1790 adet stroboskobi kayd retrospektif olarak incelenmi tir. Ya lar 7 ile 86 aras nda de i en organik ses bozuklu u tespit edilen 584 vaka çal maya dahil edilmi tir. Vakalar n ya , cinsiyetleri lezyonun tipi, görüldü ü y l kaydedilmi tir. Hastalar n lezyon tipi ve lezyonlar n cinsiyete ve y llara göre da l m kar la t r lm t r. Sonuçlar: Organik patolojisi bulunan 584 hastan n %52.2 si kad n %41.8 i erkekti. Lezyon da l m %25.7 polip, %17 reinke %15.9 nodül olarak tespit edilmi tir. Kord vokal nodülü yaln zca kad nlarda ve çocuklarda görülmü tür. Polip ise erkeklerde kad nlara göre istatiksel olarak anlaml oranda daha fazla görülmü tür (S ras yla %38.9, %18; p<0.05). Kist yeti kin kad nlarda erkeklere göre daha fazla oranda saptanm t r bu oran istatiksel olarak anlaml bulunmu tur (S ras yla % 7.9, %3.3; p<0.05). Presbilarinks yeti kin kad nlarda erkeklere göre istatiksel anlaml o...
Background The etiopathogenesis of Fibromyalgia Syndrome (FMS) still remains unclear. Helicobacter Pylori (HP) has been implicated as playing a role in a variety of extragastric diseases including FMS. However, studies on the association of HP and FMS are in limited number (1). Objectives We have aimed to investigate the difference between HP infected and not infected patients for the presence of FMS to explore possibility of a link between HP infection and FMS. Methods After obtaining Ethic Committe approval of our Institution, patients who presented to Gastroenterology Unit and tested HP as a part of their work-up were also referred to Rheumatology. At the same day of Gastroscopy, patients were evaluated by the same Rheumatologist. Patients with serious internal or psychiatric diseases or taking medications that would interfere with FMS symptoms were excluded. Patients indicated painful or tender areas that present over the last week according to widespread pain index (WPI) of 2010 modified FMS Diagnostic Criteria (2). If 3 or more areas were indicated, patients were further evaluated for the presence of FMS. Patients who were diagnosed FMS based on 2010 Diagnostic Criteria were also evaluated according to 1990 FMS Classification Criteria (3). Physical examinations and laboratory work-up were done to exclude conditions that would cause widespread pain. HP was tested with rapid urease test-HelicotecUT Plus, and biopsy specimens were obtained from antrum and the body of stomach (2 from each sites). Test reading were done up to 24 hours. Statistics: Quantitative data are expressed as means and standard deviations, and for the comparison of variables between groups, Student's t test was used. For the comparison of qualitative data, Pearson's chi-square test, Fisher's exact test and the Continuity Correction (Yates) test were used. P values <0.05 were considered as statistically significant. Results We studied 95 cases; 53 (55.8%)HP positive and 42 (44.2%) HP negative. The age of patients ranged between 18 and 65 years, mean age 36.16±11.62 years. 51 patients (53.7%) were males and 44 (46.3%) were female. In 53 cases (55.8%), pain was indicated at least in one area of WPI. There was no statistically significant difference for the age between HP positive and negative patients (p=063). HP positivity in men (68.6%) was significantly higher than women (40.9%) (p=0.012). FMS was diagnosed in 6 cases (6.3%); 2 (3.8%) of HP positive patients and 4 (% 9.5) of HP negative patients, and the difference was not statistically significant (p=0.4). Conclusions In a group of HP infected patients, we could not find higher rate of FMS compared to not infected patients. Our findings do not give any clue for an association between HP infection and FMS. References Akkaya N, Akkaya S, Polat Y, Turk M, Turk T, Turhal E, Sahin F. Helicobacter pylori seropositivity in fibromyalgia syndrome. Clin Rheumatol 2011;30:43-9. Wolfe F, Clauw DJ, Fitzcharles MA et al. Fibromyalgia criteria and severity scales for clinical and epidemiolo...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.