PURPOSE In 2016, there were 1,308,061 cases of cancer being treated in Indonesia, with 2.2 trillion rupiahs spent, amounting to $486,960,633 in US dollars (purchasing power parity 2016). The high burden of cancers in Indonesia requires a valid data collection to inform future cancer-related policies. The purpose of this study is to report cancer epidemiological data from 2008 to 2012 based on Hospital-Based Cancer Registry (HBCR) data from Cipto Mangunkusumo Hospital, Indonesia. METHODS This was a descriptive study with cross-sectional design. Data were collected from Cipto Mangunkusumo Hospital HBCR 2008-2012. Demographical, diagnostic, stages of cancer, and histopathological types of cancer data were extracted. RESULTS After screening, 18,216 cases were included. A total of 12,438 patients were older than 39 years of age (68.3%), with a female-to-male ratio of 9:5. Most patients have cancers at advanced stages (stages III and IV, 10.2%). The most common sites of cancer were cervix uteri (2,878 cases, 15.8%), breast (2,459 cases, 13.5%), hematopoietic and reticuloendothelial systems (1,422 cases, 7.8%), nasopharynx (1,338 cases, 7.4%), and lymph nodes (1,104 cases, 6.1%). CONCLUSION From this HBCR, cancer incidence in female was almost twice the incidence in male, largely because of the burden of cervical and breast cancers. The cervix uteri as one of the top five cancer sites based on this HBCR, 2008-2012, are still approximately consistent with Global Cancer Incidence, Mortality and Prevalence 2018, which portrayed that Indonesia has been severely afflicted by cervical cancer cases more than any other Association of Southeast Asian Nations countries. The HBCR could serve as a robust database of epidemiological data for cancer cases in Indonesia.
Introduction.Various cancer registrations and reports had confirmed the higher proportion of young women with breast cancer in Asian countries. This mandates special attention for clinician since this group of patients need different management approach, especially regarding the more aggressive biological behavior, worse prognosis and the escalating psychosocial burden that young women endure. We conducted a study to describe the clinicopathological characteristics of young-aged breast cancer in Indonesia and its relationship with overall survival. Method. This study is a survival analysis using samples all young-aged women with histologically-proven cancer diagnosis that underwent treatment (surgery and/or chemotherapy and/or irradiation and/or hormonal therapy) since January 2008 to August 2015. Data were collected from both medical records and interview. Data were analyzed using SPSS Results. Young-age women comprise 35% of total breast cancer patients, with most cases were in the locally advanced stage, histologic type NST, grade 2, no lymphovascular invasion, positive hormone receptors, negative HER2 status, high Ki-67 and Luminal B subtype. The 5-year overall survival rates were 64%; variables that showed statistically significant correlation was tumor size, nodal status, metastasis status and clinical stage. Histologic type NST, grade 2, positive lymphovascular invasion, high Ki-67 and positive HER2 were related to survival, but this correlation was not statistically significant. Conclusion. Overall 5-year survival rates of young-aged breast cancer at dr. Cipto Mangunkusumo General Hospital was 64%, much lower that reported figures from literatures and other countries' reports. Clinical stage was the only variable with statistically significant correlation. Luminal B subtype was observed the most, but the worst survival was found in the HER2 subtype group.
Solitary bone plasmacytoma is a localized neoplasm in the bone consisting of abnormal plasma cells. We herein report an unusual presentation of solitary bone plasmacytoma in the mandible. A 57-year-old woman with the lump at the right jaw, which was increased gradually for 13 years. The diagnosis build based on clinical, radiological, and histopathological findings. She underwent radiotherapy before surgery using a 50 Gy of irradiation for 25 times results in a partial response. A hemimandibulectomy proceeded, followed by immediate reconstruction using a free vascularized fibular flap. Complete resection may eliminate monoclonal proteins in serum and reduce disease progression into multiple myeloma. The patient remains to follow up regular visits to the oncology surgery clinic in RSCM, with no recurrence of disease in six months postoperative.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.