Objective: This study investigated the relation between osteoporosis and vitamin D levels and the disease activity in patients with psoriatic arthritis (PsA). Materials and methods:In this study, 58 patients with PsA and 58 healthy controls were included. Bone mineral density (BMD) measurements of patients and controls were performed using dual-energy X-ray absorptiometry. Complete blood count, serum 25(OH)D3, parathormone, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), total calcium, ionized calcium, and phosphorous levels of all participants were measured. Disease activity was evaluated using the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Disease Activity Index for Reactive Arthritis (DAREA), and the Disease Activity Score 28 (DAS28). The functional status was evaluated using the Health Assessment Questionnaire for the spondyloarthropathies (HAQ-S), and enthesopathy was evaluated using the Maastricht Ankylosing Spondylitis Enthesitis Score (MASES).Results: BMD values of the patients were significantly lower than those of the controls. There was a negative but statistically insignificant relationship between the lateral lumbar BMD values of the patients and clinical activity signs. Vitamin D levels of the patients were significantly lower than those of the controls. Although there was no correlation between vitamin D levels and ESR and CRP levels, a negative but statistically insignificant relation was found between vitamin D levels and BASDAI, DAREA, and DAS28. The level of CRP, BASDAI, MASES, DAREA, HAQ-S, and DAS28 scores were higher in the patients with osteoporosis; however, none of the differences were statistically significant. Conclusion:In this study, the incidence of osteoporosis was higher and vitamin D levels were lower in patients than in controls.
Aim: Type 2 diabetes mellitus (DM), osteoporosis and obesity are increasingly common diseases due to the increase in the elderly population and the change in eating habits. However, the relationship between diabetes, obesity and osteoporosis has not been fully clarified in studies in the literature. In our study, it was investigated whether the combination of diabetes and obesity caused osteoporosis and increased fracture risk. Material and Method: Our study was carried out with a total of 95 patients between the ages of 40 and 80, including 24 males and 71 females, who were tested due to the preliminary diagnosis of osteoporosis and diagnosed with type 2 DM in the physical medicine and rehabilitation outpatient clinic. The demographic characteristics, body mass index (BMI), bone mineral density (BMD) measurements, X-ray imaging, and fracture risk assessment scale (FRAX) calculations of patients were performed. Groups were compared in terms of BMD and FRAX according to the BMI classification. Results: BMD and FRAX hip values were higher in the obese group according to the BMI classification compared to the pre-obese/normal group (p0.05). Conclusion: As a result of our study, it was observed that type 2 DM and obesity were associated with increased fracture risk despite high BMD values.
Aim: It was aimed to investigate the effect of transcutaneous electrical nerve stimulation (TENS) treatment, which is widely used for pain, on cardiac electrical activity by using new proarrhythmogenic markers that give an idea on cardiac arrhythmia. Material and Method: Forty patients (21 females, 19 males, mean age 56.60±10.38) who applied to our outpatient clinic with the complaint of pain in the left shoulder or limitation of motion were included in our study. A fifteen-session physical therapy program was applied to the patients. Twelve-lead electrocardiography (ECG) was performed before treatment, at the end of the first day of treatment, and after treatment; and heart rate, QT interval (cQT) corrected according to Bazett's formula, Tp-e/QT and electrophysiological balance index (iCEB) ratio were measured. The relationship of the measurements before treatment-first day after treatment, before treatment-fifteenth day after treatment and first day after treatment-fifteenth day after treatment was evaluated by Paired-Samples T test analysis. Results: In our study, when heart rate, cQT, Tp-e/QT and iCEB values were statistically analyzed, no significant difference was observed between measurements, since p>0.05. Conclusion:In our study, when the heart rate, new proarrhythmogenic markers cQT, Tp-e/QT and iCEB values were examined in patients who received physical therapy to the left shoulder region, it was seen that TENS treatment did not have a significant effect on cardiac rhythm.
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