The ethanolic extract of sage {Salvia officinalis L.} was separated into five fractions through reextraction with supercritical CO2. Further fractionation of the most active antioxidant fractions by means of liquid chromatography, with silicic acid as absorbent, yielded 2H-10,4a-(epoxy methano}-phenantren-12-one-l,3,4,9,10,10ahexahydro-5,6-dihydroxy-9a-ethoxy-1,1-dimethyl-7-(1methylethyl), (rosmanol-9-ethyl ether}. The same compound was isolated from the alcoholic extract of the hyssop {Hyssopus officinalis L.}. Rosmanol-9-ethyl ether was shown to be one of the active antioxidant components in sage and hyssop, with activity much greater than butylated hydroxytoluene (BHT}. KEY WORDS: Hyssop extract, natural antioxidants, rosmanol-9-ethyl ether, sage extract, supercritical CO 2 extraction. Natural products, isolated from spices, can act as antioxidants either alone or synergistically with chemical additives. In 1977, Chang et al. (1} reported a patented
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