BRmTS 1247 MDICAL JOURNAL should be avoided. Non-barbiturate hypnotics on the whole seem to carry a much lesser risk of habit-formation and addiction, though in the case of unstable alcoholics such a happening can never be excluded. Among the non-barbiturate hypnotics methyprylone, glutethimide, and the newer thalidomide (" distaval ") and methaqualone hydrochloride (" melsedin ") have so far in our experience proved quite suitable for alcoholics. In the case of thalidomide, the possibility of peripheral neuropathy as a toxic manifestation'21'4 must be kept in mind, but several of our patients with evidence of alcoholic neuropathy showed a satisfactory response to treatment though receiving thalidomide, as in the case recently reported by etc.,
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