Significant differences in mean T2 values and texture parameters were found between subregions in this carefully selected asymptomatic population, which suggest that there is normal variation of T2 values within the knee joint. The clinically relevant subregions were found to be robust as demonstrated by the overall high repeatability.
Objective:A standardized definition of normative T2 values across the articular surface of the hip must be defined in order to fully understand T2 values for detecting early degeneration. Therefore, in this article, we seek to lay foundational methodology for reproducible quantitative evaluation of hip cartilage damage using T2 mapping to determine the normative T2 values in asymptomatic individuals.Design:Nineteen prospectively enrolled asymptomatic volunteers (age 18-35 years, males 10, females 9, alpha angle 49.3º ± 7.2º) were evaluated with a sagittal T2 mapping sequence at 3.0 T magnetic resonance imaging. Acetabular and femoral cartilage was manually segmented directly on the second echo of the T2 mapping sequence by 3 raters, twice. Segmentations were divided into 12 subregions modified from the geographic zone method. Median T2 values within each subregion were compiled for further analysis and interrater and intrarater reliability was assessed.Results:In the femur, the posterior-superior subregion was significantly higher (P ≤ 0.05) than those in the posterior-inferior and anterior-inferior subregions. In the acetabulum, the anterior-inferior subregion was significantly higher (P ≤ 0.001) than in the anterior-superior, middle, and posterior-inferior subregions. T2 values of the posterior-superior subregion were significantly higher (P ≤ 0.05) than the anterior-superior, middle, and posterior-inferior subregions. Interrater agreement was generally fair to good.
Positron emission tomography (PET) use is increasing; however, optimal utilization in gynecologic oncology remains unclear. PET is expensive, has limited anatomic detail, and it may be difficult to differentiate benign ovarian lesions from malignant lesions when PET is used. A 43-year-old female volunteer's PET scan revealed increased uptake in the left ovary. A subsequent extensive evaluation was entirely normal; however, the patient pursued excision with only a corpus luteum on final pathology. There is a dearth of information regarding PET scan ovarian abnormalities in asymptomatic premenopausal patients, as much of the literature focuses on women with a known ovarian lesion or cancer. Our case represents an increasingly common situation: evaluation and management of an asymptomatic woman with a positive PET scan. As more clinicians encounter PET scan abnormalities, it is imperative that the medical literature documents the limitations of this technology, especially in premenopausal women.
Background: The prevalence of findings on shoulder magnetic resonance imaging (MRI) is high in asymptomatic athletes of overhead sports. Purpose/Hypothesis: The purpose of this study was to determine the prevalence of atypical findings on MRI in shoulders of asymptomatic, elite-level climbers and to evaluate the association of these findings with clinical examination results. It was hypothesized that glenoid labrum, long head of the biceps tendon, and articular cartilage pathology would be present in >50% of asymptomatic athletes. Study Design: Cross-sectional study; Level of evidence, 3. Methods: A total of 50 elite climbers (age range, 20-60 years) without any symptoms of shoulder pain underwent bilateral shoulder examinations in addition to dedicated bilateral shoulder 3-T† MRI. Physical examinations were performed by orthopaedic sports medicine surgeons, while MRI scans were interpreted by 2 blinded board-certified radiologists to determine the prevalence of abnormalities of the articular cartilage, glenoid labrum, biceps tendon, rotator cuff, and acromioclavicular joint. Results: MRI evidence of tendinosis of the rotator cuff, subacromial bursitis, and long head of the biceps tendonitis was exceptionally common, at 80%, 79%, and 73%, respectively. Labral pathology was present in 69% of shoulders, with discrete labral tears identified in 56%. Articular cartilage changes were also common, with humeral pathology present in 57% of shoulders and glenoid pathology in 19% of shoulders. Climbers with labral tears identified in this study had significantly increased forward elevation compared with those without labral tears in both active ( P = .026) and passive ( P = .022) motion. Conclusion: The overall prevalence of intra-articular shoulder pathology detected by MRI in asymptomatic climbers was 80%, with 57% demonstrating varying degrees of glenohumeral articular cartilage damage. This high rate of arthritis differs significantly from prior published reports of other overhead sports athletes.
Background:Imaging of the femoral trochlea has been inherently difficult because of its
convex anatomy.Purpose/Hypothesis:The purpose of this study was to compare the diagnostic utility of a standard
axial magnetic resonance imaging (MRI) sequence with an axial-oblique MRI
sequence of the knee for the detection of trochlear articular cartilage
lesions on a high-field 3-T MRI scanner. We hypothesized that axial-oblique
MRI scans of the knee obtained along the true axis of the trochlea would
significantly improve the detection of high-grade cartilage lesions.Study Design:Cohort study (diagnosis); Level of evidence, 2.Methods:Patients who underwent MRI and subsequent surgery for any indication were
prospectively enrolled into this study between June 2014 and February 2015.
The articular cartilage of the trochlea was evaluated independently by 3
raters on axial and axial-oblique MRI and compared with arthroscopic
findings (gold standard). The interrater and intrarater reliability of mild
(International Cartilage Repair Society [ICRS] grades 1 or 2) and severe
(ICRS grades 3 or 4) lesions on MRI were assessed as well as the
sensitivity, specificity, positive predictive value, and negative predictive
value.Results:A total of 99 knees in 96 patients were included in the study. Interrater and
intrarater agreement for the identification of severe lesions were moderate
to good on the proximal trochlea and fair to moderate on the distal
trochlea. No significant differences in sensitivity were found between axial
and axial-oblique scans for any grade of lesion (55% vs 51%, respectively;
P = .700) or for severe lesions (61% vs 52%,
respectively; P = .289). Similarly, specificity for
detecting severe lesions was not significantly different between axial and
axial-oblique scans (95% vs 87%, respectively; P = .219).
Last, no significant differences in sensitivity or specificity were found
between MRI sequences when separately evaluating proximal and distal
trochlear lesions (all P > .05).Conclusion:The axial-oblique sequence was unable to improve the sensitivity of MRI in
detecting articular cartilage lesions on the trochlea. Both conventional
axial and axial-oblique sequences, reviewed independently of the complete
MRI series, had low sensitivity in detecting trochlear articular cartilage
lesions. For this reason, clinicians should utilize all MRI planes to
evaluate the articular cartilage of the trochlea. Future studies should
focus on improving MRI techniques for detecting and characterizing cartilage
lesions of the trochlea.
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