OBJECTIVES To address donor attitudes and reasons for selecting either laparoscopic or open donor nephrectomy (LDN, ODN), as despite the increased interest in laparoscopic procedures, organ donation continues to lag behind the demand for organs, and many new initiatives have failed to reduce the gap. PATIENTS AND METHODS This case series comprised a 10‐year review of medical records and a transplant database on donor demographics, analgesic requirements, postoperative complications and length of hospital stay. A structured telephone interview was conducted for all live donors to evaluate donor awareness, reasons for selecting LDN and the psychosocial impact of DN on donors’ rehabilitation. RESULTS Between 1995 and 2004, 38 LDN and 38 ODN were carried out; 70% were women in both groups, with a respective mean age of 44.4 and 47.1 years. Three LDNs were converted to ODN due to technical difficulties. The mean operative duration for LDN (194.8 min) was 78 min longer than for ODN (116.8 min). As expected, the mean analgesia requirement and length of hospital stay was less for LDN than ODN, by 55.4 mg of morphine equivalent and 2.3 days. Although all renal donors were aware of the option of LDN, one patient chose ODN due to safety concerns. The primary source of donor information was derived predominantly from the donor assessment process. The main reason for choosing LDN was the earlier return to work (54%), followed by less postoperative pain (33%). In general, there was minimal psychosocial impact after renal transplantation and the overall donor experience was very positive (85%). CONCLUSION LDN has remained a safe, less‐invasive but effective technique for allograft procurement, with minimal morbidity. Overall, there is less postoperative pain and fewer surgical complications, and an earlier return to normal functioning. The level of satisfaction with the whole renal donation process was very positive, with minimal psychosocial impact.
Summary Up to 45% of esophageal atresia (EA) patients undergo fundoplication during childhood. Their esophageal dysmotility may predispose to worse fundoplication outcomes compared with patients without EA. We therefore compared fundoplication outcomes and symptoms pre- and post-fundoplication in EA patients with matched patients without EA. A retrospective review of patients with- and without EA who underwent a fundoplication was performed between 2006 and 2017. Therapeutic success was defined as complete sustained resolution of symptoms that were the reason to perform fundoplication. Fundoplication indications of 39 EA patients (49% male; median age 1.1 [0.1–17.0] yrs) and 39 non-EA patients (46% male; median age 1.3 [0.3–17.0] yrs) included respiratory symptoms, brief resolved unexplained events, typical symptoms of gastroesophageal reflux disease, recurrent strictures and respiratory problems. Post-fundoplication, therapeutic success was achieved in 5 (13%) EA patients versus 29 (74%) non-EA patients (P<0.001). Despite therapeutic success, all 5 (13%) EA patients developed postoperative sustained symptoms/complications versus 12 (31%) non-EA patients. Eleven (28%) EA patients versus 3 (8%) non-EA patients did not achieve any therapeutic success (P=0.036). Remaining patients achieved partial therapeutic success. EA patients suffered significantly more often from postoperative sustained dysphagia (41% vs. 13%; P=0.039), gagging (33% vs. 23%; P<0.001) and bloating (40% vs. 17%; P=0.022). Fundoplication outcomes in EA patients are poor and EA patients are more susceptible to post-fundoplication sustained symptoms and complications compared with patients without EA. The decision to perform fundoplication in EA patients with proven gastroesophageal reflux disease needs to be made with caution after thorough multidisciplinary evaluation.
day of embryo transfer were used to estimate the linear regression beta and 95% confidence interval (CI) of mean initial hCG values and 2-day percent hCG rises.RESULTS: Mean initial serum hCG values were inversely correlated with BMI class (Table) (P-value test for linear trend <0.001). Obese women were more likely to have low initial serum hCG values (<100 mIU/mL) and this increased across BMI classes, ranging from 1.4% of normal weight patients to 25% of patients with BMI >40 kg/m 2 (p-value test for linear trend¼0.002). However, mean 2-day percent hCG rises were similar between normal weight and obese patients, and were normal (>53%) in all groups.CONCLUSIONS: When compared with normal weight patients, obese patients had significantly lower initial serum hCG values, but still achieved singleton live births. Mean 2-day percent rises in hCG were normal across all BMI classes. Rate of hCG rise remains the mainstay of monitoring early pregnancies following IVF, particularly as initial hCG values may lack sensitivity for live birth in obese patients. Elevated BMI is associated with increased blood volume, which may affect serum hCG concentration. Given the impact of BMI on this crucial blood test, future studies should explore whether BMI impacts the interpretation of other serum analytes.P-717 Wednesday, OBJECTIVE: To compare the ectopic pregnancy (EP) risk between blastocyst transfer cycles and cleaved embryo transfer cycles of in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) in women with previous EP.DESIGN: Retrospective cohort study. MATERIALS AND METHODS: A total of 1,188 women who had previous EP and underwent frozen-thawed embryo transfer (FET) cycles of IVF/ICSI in the period between November 2007 and January 2015 were enrolled. After excluding those with uterine abnormities, uterine disorders, incomplete cycle information and other conditions that were not suitable for analysis, finally 1,148 pregnancies from 1,097 women were further analyzed. In the univariate analysis, the EP rate was compared by patient and treatment characteristics including maternal age, presence of prior full-term birth, Fallopian tubal diseases, previous Fallopian tubal surgery, polycystic ovary syndrome, endometriosis and male factor infertility, type of endometrial preparation, number and stage of embryos transferred, endometrial thickness on embryo transfer day and year of treatment. In order to account for the correlation between all pregnancies reported by the same woman, we used goodness of fit to specify the best fitted generalized estimated equation regression models to calculate unadjusted and adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for the association between EP and significant characteristics selected from the univariate analysis (P<0.20) plus year of treatment. Statistical analyses were carried out by SPSS version 23.0. In the univariate analysis, Chi-square test or Fisher's exact test was applied to perform rate comparisons as appropriate. In the multivariate analysis, P<0.05 ...
To report the rare occurrence of cardiac cystic mass detected intra-operatively despite the best of surgical work up preoperatively. The incidental finding of cardiac lymphangioma during routine cardiac bypass graft in an adult is rare but this needed to be dealt with expediently to avoid latter complications or need for operation in later date.
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