Objective: In this study we aimed to define clinical, radiologic and pathological specialties of patients who applied to General Surgery Department of Atatürk University Medical Faculty with granulomatous mastitis and show medical and surgical treatment results. With the help of this study we will be able to make our own clinical algorithm for diagnosis and treatment. Materials and Methods:We searched retrospectively addresses, phone numbers and clinical files of 93 patients whom diagnosed granulomatous mastitis between a decade of January 2001 -December 2010. We noted demographic specialties, ages, gender, medical family history, main complaints, physical findings, radiological and laboratory findings, medical treatments, postoperative complications and surgical procedures if they were operated; morbidity, recurrence and success ratios, complications after treatment for patients discussed above. Results:In this study we evaluated 93 patients, 91 females and 2 males, with granulomatous mastitis retrospectively who applied to General Surgery Department of Atatürk University Medical Faculty between January 2001 and December 2010. Mean age was 34.4 years. The diagnosis was confirmed by histopathologic examination of the lesions. Seventy three patients had idiopathic granulomatous lobular mastitis and 20 patients had specific granulomatous mastitis IGM (18 tuberculosis mastitis, 1 alveolar echinococcosis and 1 silk reaction). All the patients had surgical debridement or antibiotic, and anti-inflammatory treatment with results bad clinical response before applied our clinic. Conclusion:Empiric antibiotic therapy and drainage of the breast lesions are not enough for complete remission of idiopathic granulomatous mastitis. The lesion must be excised completely. In selected patients, corticosteroid therapy can be useful. In the patients with tuberculous mastitis, abscess drainage and antituberculous therapy can be useful, but wide excision must be chosen for the patients with recurrent disease. Keywords: Mastitis, granulomatous mastitis, tuberculosis mastitis ÖzetAmaç: Atatürk Üniversitesi Tıp Fakültesi genel cerrahi kliniğine baş-vuran ve granülomatöz mastit tanısı alan hastaların klinik, patolojik ve radyolojik özelliklerini belirlemek ve bu hastaların medikal ve cerrahi tedavi sonuçlarını bildirmektir. Bu sayede tanı yöntemleri ve tedavi algoritması üzerinde kliniğimiz deneyimine göre hareket etmek mümkün olacaktır. Gereç ve Yöntem:Ocak 2001 -Aralık 2010 arasındaki 10 yıllık dönem-de histopatolojik olarak granülomatöz mastit tanısı alan 93 olgunun hastane dosyalarına, adres ve telefon kayıtlarına ulaşıldı, dosyaları retrospektif olarak incelendi. Olguların demografik özellikleri yaşları, cinsiyeti, aile hikayesi, şikayetleri, fizik muayene bulguları, radyolojik ve laboratuvar bulguları, medikal tedavisi, ameliyat edilmiş ise ameliyatın şekli, ameliyat sonrası komplikasyonlar, tedavi sonrası morbidite ve nüks oranları not edildi, başarı oranları ve komplikasyonları çıkarıldı.Bulgular: Çalışma yaşları 20 ile 73...
Isolated pancreatic hydatid cysts are a rare parasitic disease even in endemic areas. It is difficult to discriminate primary pancreatic hydatid cysts from other cystic and solid lesions of the pancreas. This is a case report of an incidental isolated pancreatic hydatid cyst. A heterogeneous cystic lesion in the body of the pancreas was identified on magnetic resonance imaging of a patient previously diagnosed patient with cholelithiasis, and because of the malignant possibility of the lesion, splenectomy with distal pancreatectomy and cholecystectomy was performed. The histopathologic diagnosis was reported as a hydatid cyst. Pancreatic hydatid cysts should be kept in mind in the differential diagnosis of pancreatic pseudocysts and cystic malignancies. (Turkiye Parazitol Derg 2015; 39: 75-7) Keywords: Hydatid cyst, incidental, pancreas Received: 19 Temmuz 2013Accepted: 4 Eylül 2014 ÖZETİzole pankreas kist hidatiği endemik bölgelerde bile çok nadir görülen paraziter hastalıktır. Sadece pankreasta yerleşen primer kist hidatiklerin pankreasın diğer kistik ve solid lezyonlarından ayırımı güçtür. Yazımızda tesadüfen tespit edilen izole pankreas kist hidatiği vakası sunulmuştur. Kolelitiazisi mevcut olan hastaya çekilen magnetic resonance imaging (MRI)'de pankreas gövdesinde heterojen içerikli kistik lezyon tespit edilmesi üzerine mevcut lezyonun pankreasın kistik malignitesi olduğu düşünülerek hastaya splenektomi ile distal pankreatektomi ve kolesistektomi yapılmıştır. Histopatolojik tanı kist hidatik şeklinde rapor edilmiştir. Pankreas psödokistlerinin ve kistik malignitelerin ayırıcı tanısında pankreas kist hidatiği akılda tutulmalıdır. (Turkiye Parazitol Derg 2015; 39: 75-7)
Introduction and Aim: The purpose of this study was to determine the value, in terms of diagnosis, resectability and prognosis of pentraxin-3 (PTX3), interleukin-8 (IL-8) and vascular endothelial growth factor (VEGF) in cases of gastric adenocarcinoma, an important condition both worldwide and in Turkey, and to determine their levels in order to contribute to elucidating the pathogenesis of the disease. Materials and Methods: Serum was separated from blood specimens collected from 45 patients diagnosed with gastric adenocarcinoma and from a 30-member healthy control group. Serum PTX3, IL-8 and VEGF levels were studied by ELISA method. Results: Serum PTX3 values differed significantly between the patient group and the control group (p<0.05). Serum IL-8 values also differed significantly between the patient group and the control group (p<0.05). A significant difference was also observed between serum VEGF values in the patient group and the control group (p<0.05). Significant correlation was determined between serum PTX3 and VEGF (p<0.01; r=0.833), between serum PTX3 and IL-8 (p<0.01; r=0.818), and between serum VEGF and IL-8 (p<0.01; r=0.803), measurements when the entire study population was evaluated irrespectively of groups. Conclusion: Serum PTX3, IL-8 and VEGF levels decreased in cases of gastric adenocarcinoma compared to the control group, and their levels affected one another.
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