Advances in the biology of Ewing sarcoma, which continues to be an important cause of mortality, have caused an increase in information in the literature related to the underlying molecular base of the disease and discussions of new treatment approaches. In this study, we aimed to comprehensively analyze the published scientific articles on Ewing sarcoma. The Web of Science database was used to obtain and statistically analysis articles on Ewing sarcoma that were published between 1980 and 2021. Maps of network visualization were used to reveal trending topics, global collaborations, and the most effective studies. Correlation analysis was performed using Spearman's correlation coefficient. A total of 3236 articles were analyzed. The first 3 countries that contributed the most to the literature and cooperated most intensively were USA (1194, 36.8%), Germany (293, 9%), Italy (254, 7.8%). Pediatric Blood & Cancer (n = 122), Cancer (87), Journal of Pediatric Hematology Oncology (71) were among the top 3 journals with the most articles. The most active author was Piero Picci (n = 94). High-income countries have a great effect on the literature on this subject. The most studied trend topics in recent years were pediatric oncology, EWS RNA Binding Protein 1 (EWSR1), EWSR1-FL1, epigenetics, bioinformatics, microRNA, gene expression, metastasis, migration, biomarker, immunotherapy, survival, outcomes, surveillance epidemiology and end results (SEER), nomogram, temozolomide, irinotecan, and drug resistance. Genetic studies, metastasis, immunotherapy, life analyses/nomogram based on new data obtained from SEER, and chemotherapy with irinotecan and temozolomide combination, were seen to be the topics researched in recent years.Abbreviations: ES = Ewing sarcoma, EWSR1 = EWS RNA Binding Protein 1, GDP = gross domestic product, GDP per capita = gross domestic product per capita, HDI = human development index, NC = number of co-citation, SCI-Expanded = Science Citation Index Expanded, SEER = surveillance epidemiology and end results.
Objective: A retrospective examination was made of tibia shaft fractures treated with tibia intramedullary nail (IMN) (Dunitech Nite Tibial IMN Oliga Med Ankara-Turkey), which are designed with distal retractable claws, unlike classic imtramedullar nails. It was aimed to evaluate the effect on healing of the nail diameter and the distance between the fracture line and the proximal and distal fixation points of the IMN. Material and Method: The study included 28 patients (18 males, 10 females; mean age 43.75 (18-69) years) treated with distal retractable claw tibia IMN for a diagnosis of unilateral tibia diaphyseal fracture between January 2020 and January 2022. The midpoint of the fracture line (F), the proximal fixation point of the locking screw (S), the distal fixation point of the retractable claw (T), and the isthmus mid-point (I) were determined as reference points. The FT, ST, and IT distances, the nail diameter (ND) and isthmus diameter (ID) were measured and the FT/ST ratio was calculated. Statistical evaluations were made of the relationships between the diameter and length measurements and the visual analog scale (VAS) and radiographic union score for tibia (RUST) scores at the end of one year. Results: No statistically significant correlation was determined between the RUST and VAS scores and the diameter measurements or the distance between the proximal and distal fixation points of the IMN. Conclusion: There was no effect on the fracture healing scores of the nail diameter or the distance between the proximal and distal fixation points in tibia shaft fractures treated with a tibia nail with distal retractable claws. The nail design with retractable claws provides strong fixation and stable fracture healing. The operating time is shorter resulting in less radiation exposure. Keywords: Tibia Fracture, İntramedüller Nail, Fracture Healing
Objectives The aim of this study was to evaluate the relationship between the length of the protruded screws from the dorsal cortex and extensor tendon damage in all compartments. Patients and methods Between May 2020 and April 2021, a total of 29 patients (13 males, 16 females; mean age: 52.3±13.0 years; range, 30 to 78 years) who were operated and followed in our clinic for AO A2 and A3 distal radius fractures were included in this prospective study. Surface ultrasound (US) imaging was made to the dorsal sides of both wrists of the operated patients at different timepoints postoperatively. The length of screws with radius dorsal cortex penetration and the presence of tendinitis were recorded. Results In 15 of 23 patients, the presence of 29 protruding screws was accompanied by tendinitis and, in eight patients, no tendinitis was observed, despite the partial protrusion of screws. A statistically significant correlation was found between the screw protrusion and presence of tendinitis (p<0.05). The number of protruding screws and tendinitis were seen mostly in the second compartment. There was a statistically significant correlation between the protruding screw length of >1.6 mm and the presence tendinitis (p<0.05). Conclusion Dorsal cortex screw protrusions in the application of volar plate for distal radius fractures can cause tendinitis. Screw protrusions occur more frequently in the second compartment and the development of tendinitis in this compartment is associated with a screw length of >1.6 mm. Screw penetration can be easily identified with intraoperative US to prevent tendinitis and potential tendon ruptures.
Aim: The aim of this study a retrospective comparison was the clinical and radiological results results of patients with femoral shaft fracture made oftreated with three different types of intramedullary nail (IMN). Material and Method: The study included 54 patients operated on in our clinic because of femoral shaft fracture. The records were retrospectively examined of 18 patients applied with locked IMN (LIMN), 17 with blade expandable IMN (BEIMN), and 19 with talon distalfix IMN (TDIMN). The groups were compared statistically in respect of age, gender, BMI, affected side, operating time (mins), radiation exposure (number of shots), time to union (weeks), visual analog scale (VAS) score, soft tissue problems associated with implant irritation, amount of shortening (mm), coronal, sagittal and torsional angulation (degrees). Results: The mean VAS score of the TDIMN group was determined to be statistically significantly higher than that of the LIMN and BEIMN groups (p=0.008, p=0.045). The operating times were similar in the BEIN and TDIMN groups (p=0.768) and significantly shorter than in the LIMN group (p
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