To investigate the possible relationship between gallbladder cholesterolosis and acute pancreatitis, we studied 3797 cholecystectomy specimens and found 55 cases of gallbladder cholesterolosis unassociated with biliary lithiasis. From the reviewed case notes, 27 of these patients presented with recurrent attacks of acute pancreatitis which disappeared after cholecystectomy (follow-up 65.1 months). A microscopic study revealed frank cholesterolosis in all cases with a pseudopolyp transformation of the mucosa, some polyps reaching a diameter of 2 mm. We postulate that the mechanism could be temporary impaction of cholesterolosis polyps at the sphincter of Oddi and suggest that patients with recurrent attacks of acute pancreatitis and negative aetiological investigation must be considered as at high risk of having gallbladder cholesterolosis and that they could benefit from cholecystectomy.
Fournier's gangrene is an entity that can be lethal and it is favoured by several debilitating factors. It is triggered by a urogenital or perirectal disease that has not been treated properly. Because of its poor prognosis, early diagnosis and an appropriate early and aggressive multidisciplinary intervention are essential for proper recovery.
La gangrena de Fournier es una fascitis necrosante que afecta habitualmente a la zona genital externa y perineal, con eventual extensión al abdomen, los miembros inferiores e incluso el tórax, con alta letalidad, que debe tratarse de manera agresiva en las primeras horas tras el diagnóstico. Se considera que enfermedades debilitantes como la diabetes mellitus u la obesidad favorecen su aparición. El factor desencadenante más frecuente es el absceso perianal. Objetivo: Realizar un profundo análisis descriptivo sobre los factores de riesgo y las afecciones predisponentes de la gangrena de Fournier durante toda la historia de nuestro centro, durante los últimos 12 años, así como revelar la tasa de mortalidad de éstos y el número medio de reintervenciones realizadas. Material y métodos: El estudio realizado analiza, de manera observacional y retrospectiva, a 20 pacientes diagnosticados de gangrena de Fournier, según criterios de inclusión clínicos,
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