A new master-slave binary grey wolf optimizer (MSBGWO) is introduced. A master-slave learning scheme is introduced to the grey wolf optimizer (GWO) to improve its ability to explore and get better solutions in a search space. Five high-dimensional biomedical datasets are used to test the ability of MSBGWO in feature selection. The experimental results of MSBGWO are superior in terms of classification accuracy, precision, recall,
F
-measure, and number of features selected when compared to those of the binary grey wolf optimizer version 2 (BGWO2), binary genetic algorithm (BGA), binary particle swarm optimization (BPSO), differential evolution (DE) algorithm, and sine-cosine algorithm (SCA).
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