Oral squamous cell carcinoma is associated with many known risk factors including tobacco smoking, chronic alcoholism, poor oral hygiene, unhealthy dietary habits and microbial infection. Previous studies have highlighted Candida albicans host tissue infection as a risk factor in the initiation and progression of oral cancer. C albicans How to cite this article: Engku Nasrullah Satiman EAF, Ahmad H, Ramzi AB, et al. The role of Candida albicans candidalysin ECE1 gene in oral carcinogenesis.