This study suggests that mode of delivery affects cord blood Treg cells. Higher CD4+CD25+FOXP3+ Treg cells of newborns and their mothers in vaginal delivery group and their relationship with serum cortisol levels suggest a stress phenomenon related to vaginal delivery.

Endothelial protein C receptor (EPCR) is primarily localized on the endothelial cells of large blood vessels and is very low or absent in the microvascular endothelium of most tissues. EPCR augments the thrombin/thrombomodulin-dependent activation of protein C by 5- to 20-fold. EPCR appears to be physiologically significant in the control of blood coagulation and inflammation and in the host response to gram-negative sepsis. Here, the authors report an 8-month-old boy, who had chronic liver disease due to undetermined cause. He had Staphylococcus aureus and Candida albicans sepsis and died due to gastrointestinal, lung, and peritoneal bleeding during follow-up. Serum soluble EPCR level of the patient was high (225 ng/mL) during sepsis. A homozygous 23-bp insertion of EPCR gene was demonstrated. This case indicates the importance the EPCR gene plaus in pediatric sepsis. Homozygous 23-bp insertion of the EPCR gene may be associated with a tendency to sepsis and poor outcome.

No abstract

Incomplete Kawasaki Disease Probable Associated with COVID-19: A Case Report Kawasaki disease is an acute systemic inflammatory disease affecting the medium and small vessels mostly in children under 5 years old. Although SARS-CoV2 less severely affects children, with the rapid spread of disease some new clinical aspects like Kawasaki-like disease have been reported in children affected by COVID-19. Here in we present a child with incomplete Kawasaki disease probably associated with COVID-19. Keywords: Kawasaki-like disease, incomplete Kawasaki, SARS-CoV2, COVID-19