Objectives To evaluate, in vitro, the fracture load of IPS e.max CAD occlusal veneers at thicknesses of either 0.3 or 0.6 mm luted to enamel or dentin. Materials and methods Fifty human molars were randomly distributed into five groups (n = 10): G1 ‐ healthy teeth (control); G2‐0.3‐mm‐thick veneers luted to enamel; G3‐0.6‐mm‐thick veneers luted to enamel; G4‐0.3‐mm‐thick veneers luted to dentin; and G5‐0.6‐mm‐thick veneers luted to dentin. After the luting procedures, the specimens were immersed in distilled water at 37°C for 24 hours and then subjected to mechanical loading (106 cycles at 200 N load). The specimens were subjected to a fracture load test in a universal testing machine. Two‐way ANOVA and Tukey's test (α = 0.05) were used to analyze data. Results Only the thickness factor was significant (P = .002). Values of fracture load followed by distinct letters represent significant differences (P < .05): G1 (3204 N ± 730)ab; G2 (3144 N ± 729)ab; G3 (2489 N ± 606)b; G4 (3591 N ± 776)a; and G5 (2770 N ± 598)ab. Conclusion IPS e.max ultrathin occlusal veneers luted to enamel or dentin obtained fracture load comparable to that of the healthy tooth. Clinical significance IPS e.max CAD ultrathin occlusal veneers at 0.3 or 0.6‐mm‐thick seem to provide good perspectives in relation to the clinical use.

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