Background: Atrophic skin Strain scars, also known as striae or striae distensa, are a typical variety of atrophic dermal scars that are covered by a thicker, less elastic layer of epidermis. While initially appearing pink (as striae rubra), striae distensae eventually turn white (striae alba). Platelet-rich plasma (PRP) is an effective therapeutic option for striae rubra. Objective: Assessment of possible role of platelet -rich plasma for striae distensea management. Methods: We looked for data on striae distensa and Platelet -Rich Plasma in medical journals and databases like PubMed, Google Scholar, and Science Direct. However, only the most recent or extensive study was taken into account between October 2006 and July 2021. References from related works were also evaluated by the writers. There are not enough resources to translate documents into languages other than English, hence those documents have been ignored. It was generally agreed that documents such as unpublished manuscripts, oral presentations, conference abstracts, and dissertations did not qualify as legitimate scientific study. Conclusion: New and promising in the treatment of striae distensa, platelet-rich plasma (PRP) poses no danger of hyperpigmentation or infection.
Background: Psoriasis is a chronic inflammatory, immune-mediated systemic disease with skin manifestations that typically follow a relapsing and remitting course. The most common form, plaque psoriasis, occurs in ∼80-90% of psoriatic patients. Objective: The aim of the current work was to evaluate level of serum testosterone in psoriasis male patients and its relation to severity of the disease. Patients and methods: This cohort study included a total of 35 psoriatic patients, attending At Outpatient Clinic,
Background: One of the most prevalent skin disorders is vitiligo, which causes the skin to lose its color. Only patients whose vitiligo has not responded to medicinal treatment and whose condition has stabilized should consider surgical intervention. The goal of vitiligo microneedling is to produce cytokines and growth factors that are helpful for repigmentation, in a manner analogous to the wound healing response. Objective: review of the literature on surgical therapies and micro needling roles in treatment of Vitiligo. Methods: We looked for data on Surgical Therapies, Micro needling and Vitiligo, in medical journals and databases like PubMed, Google Scholar, and Science Direct. However, only the most recent or extensive study was taken into account between February 2005 and March 2021. References from related works were also evaluated by the writers. There were not enough resources to translate documents into languages other than English, hence those documents have been ignored. It was generally agreed that documents such as unpublished manuscripts, oral presentations, conference abstracts, and dissertations did not qualify as legitimate scientific study. Conclusion:Only patients whose condition is stable despite medicinal therapy attempts undergo surgical procedures. Better effects have been shown in segmental rather than generalized vitiligo, therefore they are often reserved for hardto-treat areas like the hands, feet, lips, and nipples. The combination of microneedling with a number of topical treatments, including Tacrolimus and 5-fluorouracil, has shown promising repigmentation outcomes.
Background: This inflammatory condition affects the pilosebaceous unit, causing comedones, inflammatory papules, and pustules to appear on the face, chest, and back. Propionibacterium acnes and inflammation surrounding the pilosebaceous unit, aberrant keratinization, and increased sebum production all play a role in acne's pathophysiology. Scarring from acne and acne can lead to low self-esteem and feelings of embarrassment, all of which have a negative impact on one's overall wellbeing. Objective: To see if topical adapalene can help with post-acne scar treatment. Methods: The databases were searched for articles published in English in 4 data bases [PubMed -Google scholar-Egyptian Knowledge Bank -Science direct] and Boolean operators (AND, OR, NOT) had been used such as topical adapalene and post acne scars OR acne scar treatment and in peer-reviewed articles between January 2000 and March 2021. Documents in a language apart from English have been excluded as sources for interpretation was not found. Papers apart from main scientific studies had been excluded (documents unavailable as total written text, conversation, conference abstract papers and dissertations). Results: Anti-acne retinoid adapalene (ADP) was licensed by the FDA in 1996 for use in treating acne. It improves the appearance of the skin of the face by reducing facial lesions. Acne lesions, both inflammatory and noninflammatory, respond well to adapalene gel treatment. In terms of adverse effects, the medicine is completely safe and does not cause burning or dryness. Conclusion: It is possible that adapalene, which has been shown to be effective in the therapy of photoaging-related skin damage, could have a similar effect on the treatment of atrophic acne scars.
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