Aim To assess the effect of social isolation due to the coronavirus disease 2019 (COVID-19) pandemic on physical and mental health of Parkinson’s disease patients treated at the University Hospital Center Rijeka. Methods This cross-sectional telephone study involved Parkinson’s disease patients who had at least one control examination at University Hospital Center Rijeka in 2020 and were Croatian citizens. A questionnaire was used to obtain data on the socio-demographic characteristics and the severity of motor, anxiety, depression, and non-motor symptoms. Results The final sample included 87 patients. Most patients reported subjective worsening of motor symptoms. Patients who lived alone had worse motor scores than those not living alone. The majority of patients reported worsening of anxiety symptoms. Significant worsening of anxiety symptoms was found in patients who lived alone, had a longer disease duration, and had avoided check-ups. Fewer patients had depression symptoms than motor and anxiety symptoms. Significantly higher Hamilton Depression Rating Scale scores were observed in patients with a longer disease duration. Significant worsening of non-motor symptoms was identified in patients who lived alone, were less educated, had a longer disease duration, and had a higher Charlson comorbidity index. Conclusion Patients who live alone, have longer disease duration, are less educated, avoid check-ups, and have more comorbidities are more vulnerable to the negative effects of social isolation.
Cilj: Generalizirana distonija karakterizirana je nevoljnim kontrakcijama mišića koje dovode do pojave abnormalnog držanja i ponavljajućih pokreta. Duboka stimulacija mozga (engl. Deep Brain Stimulation, DBS) učinkovita je u distoniji otpornoj na lijekove, međutim, postoji manjak radova o dugoročnom učinku. Cilj rada je prezentirati dugoročni učinak primjene DBS-a kod pacijenata s generaliziranom distonijom. Prikaz slučaja: Pacijent je 29-godišnji muškarac s generaliziranom distonijom. Nakon rođenja primijećena je faciopareza po perifernom tipu, što je bilo pripisano cerebralnoj paralizi. Prvi simptomi, problemi s pisanjem zbog grčenja ruke, primijećeni su sa sedam godina. S petnaest godina primijećeni su problemi u govoru i pogoršanje distonije ruke. Distonične kretnje i držanje postupno se pogoršavalo, uzrokujući probleme s hodanjem i narušavajući kvalitetu života pacijenta. Simptomi se nisu popravljali unatoč primjeni farmakoterapije i kada je pacijent imao dvadeset i jednu godinu implantirane su mu elektrode u bazalne ganglije, što je drastično poboljšalo distonične kretnje, držanje i hod. Nakon operacije, unatrag osam godina, pacijent je redovito praćen, elektrode su reprogramirane uz kontinuiranu fizikalnu i terapiju govora. U dva navrata nastupio je povratak kliničke slike radi ispražnjene baterije neurostimulatora koja je prvi put zamijenjena nepunjivom, a drugi put punjivom baterijom, što je dovelo do potpunog oporavka. Zaključak: Idiopatska distonija često je neprepoznata. Iako je DBS sigurna i učinkovita metoda, nije dovoljno korištena za liječenje distonije otporne na lijekove. Ovaj slučaj pokazao je perzistentan i izvrstan učinak DBS-a na generaliziranu distoniju i pacijentovu kvalitetu života kroz duži vremenski period.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.