Diabetes Mellitus is a metabolic syndrome characterized by increased blood glucose levels. This happens due to the lack or malfunction of the hormone responsible for the absorption of glucose, insulin. DM can also be characterized by deficit of other energy sources, causing several complications in vital organs. This study has as general objective to present therapeutic interventions to reduce diabetic comorbidities. The article was carried out through a literature review, information was collected in the databases: Pubmed/Medline, Scielo, LILACS and Google Scholar. Forty results were included presenting different study designs, totaling 46 individuals studied and diagnosed with diabetes mellitus and a narrative review with 10 articles analyzed, explaining different results in order to reduce and prevent comorbidities that can be developed by the disease. This study shows efficacy in the work of the physiotherapist, in the multidisciplinary team, focused on diabetic patients, especially in the prevention of the disease, in the treatment and prevention of complications. It is necessary to indicate those with higher risks of complications and offer more adequate assistance.
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