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Introduction A case of a 48-year-old male with a nonparaneoplasic autoinmune retinopathy (nPAIR) due to chronic graft versus host disease (GVHD) after an allogenic stem cell transplantation (ASCT) is described. Case report The patient developed a bilateral rapidly progressive loss of visual acuity with bilateral optic disc edema and bilateral cystoid macular edema (CME) in the funduscopy, a ring scotoma in the visual field (VF) and photoreceptors dysfunction in the electroretinogram (ERG) 210 days after the ASCT. After ruling out other causes, the suspicion of autoimmune retinopathy (AIR) led to the study of antirecoverin antibodies which resulted positive. The exclusion of neoplasia discarded diagnosis of paraneoplasic autoinmune retinopathy (PAIR) and the temporal relationship with BMT led to the diagnosis of nonparaneoplasic autoinmune retinopathy (nPAIR) due to chronic graft versus host disease (GVHD). Oral corticosteroids led to resolution of the CME. Conclusions Diagnosis of AIR requires a high index of suspicion based on the typical findings on visual field, optical coherence tomography (OCT) and ERG, which force requesting antirecoverin antibodies. However, diagnosis is often delayed because of the need to exclude other causes. Knowing typical symptoms and signs in for a quick action is important because an earlier diagnosis and treatment will improve visual prognosis since the loss of vision already established is irrecoverable. To our knowledge, this is the first reported case in the literature of nPAIR with CME and optic disc edema due to GVHS after ASCT.
Purpose: To study if there is an association between the values obtained by anterior segment optical coherence tomography (AS‐OCT) preoperatively and postoperatively to pterygium surgery using the technique of conjunctival autograft with biological glue and its risk of recurrence.
Methods: A prospective one‐year study was carried out in 50 patients with primary pterygium who underwent excision surgery and conjunctival autograft with biological glue. All of them received the same postoperative treatment. They were followed up in the same way by taking preoperative pterygium measurements and postoperative autograft measurements by AS‐OCT and the number of recurrences was recorded. To obtain the measurements, a line was drawn perpendicular to the ocular surface at the level of the scleral spur, and the intersection of this line with the ocular surface was taken as a reference point to measure the length and the thickness of the pterygium at limbus, center and head, and the thickness of the conjunctival autograft at 1 mm (epithelial, stromal and total), 2 mm (total) and 3 mm (total).
Results: The postoperatively autograft thickness AS‐OCT measurements were associated with pterygium recurrence after conjunctival autograft with biological glue surgery.
Conclusions: There are measurable factors by AS‐OCT that can be correlated with a higher rate of pterygium recurrence after surgery.
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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