From ethyl-2-oxocyclopentanecarboxylate, we developed an asymmetric synthesis of the fluorinated dipeptide Ala-C[(Z)CFQCH]-Pro analogue of the transoid parent dipeptide. The fluorinated pseudodipeptide could be incorporated into various peptides or proteins for conformational, structural studies and biological activity studies and could also play a relevant role as an enzyme inhibitor.Laboratoire COBRA (Chimie Organique Bio-organique Re ´activite ´et Analyse),
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.