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Obese individuals have higher microalbuminuria and nonsignificantly elevated MPV, however, urine albumin loss is independent of MPV.

Hypertriglyceridemia is a rare cause of pancreatitis. In treatment pancreatic rest, lifestyle changes, medications (fibrates, n-3 polyunsaturated fatty acids, and nicotinic acid) are essential. Many experimental treatment modalities have been reported as insulin and heparin infusion and plasmapheresis. In this study we present the hypertriglyceridemia-induced pancreatitis treated with supportive care.

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Background: Patients with end stage renal disease (ESRD) have increased inflammatory and thrombotic activity. Lacks of available data exist on pro-inflammatory and prothrombotic properties of low serum 25-OH-D3 level. We aimed to analyse the association of 25-OH vitamin D with indirect markers of inflammatory and thrombotic activity in patients on haemodialysis (HD) or peritoneal dialysis (PD)

ÖzAmAç: Anksiyete ve depresyon diyaliz hastalarında en sık karşılaşılan psikolojik bozukluklardır. Bu çalışmanın amacı; kronik hastalıklarda artan anksiyete ve depresyonun hemodiyaliz (HD) ve periton diyalizi (PD) hastalarındaki varlığının tespiti, her iki grupta anksiyete ve depresyonu etkileyebilecek laboratuvar parametreleri, hastalık aktivitesi, performans durumu, sosyodemografik özelliklerinin karşılaştırılmasıdır. GErEç ve yÖntEmlEr:Yetmiş yedisi Periton Diyaliz grubu, 83'ü Hemodiyaliz grubu olmak üzere 160 son dönem böbrek yetmezliği (SDBY) olan hastaların son laboratuvar değerleri, demografik özellikleri kaydedilerek, Beck Anksiyete -Depresyon Ölçeği formu dolduruldu ve Karnofsky Performans Skalası (KPS) ile hastalık aktivasyonu belirlendi.BulGulAr: Hemodiyaliz grubunun renal replasman tedavisi (RRT), PD grubundan istatistiksel olarak anlamlı şekilde yüksekti (p<0,01). Periton diyaliz grubunda üniversite mezunu oranı, geliri 600 TL üzerindeki olguların oranı, sosyal güvencesi bulunan (SGK) olguların oranı, HD grubuna göre anlamlı şekilde yüksekti (p<0,01). Gruplar arasında depresyon şiddetleri ve skorları ile anksiyete şiddetleri ve skorları açısından istatistiksel olarak anlamlı farklılık bulunmamaktaydı (p>0,05). Kadınlarda depresyon görülme riski erkeklerden 2,66 kat yüksekti (p<0,02). Hemodiyaliz grubunda anksiyete görülen olgularda depresyon görülme riski, anksiyete görülmeyen olgulardan 4,74 kat yüksekti (p<0,01). SOnuç:Çalışmamızın sonuçları göstermiştir ki, Anksiyete/Depresyon RRT alan özellikle kadın ve yüksek eğitim düzeyine sahip hastalarda, sık olmakla birlikte HD ve PD hastalarında oran benzerdir. RRT alan hastalar iyi izlenmelidir.AnAhtAr SÖzcüklEr: Depresyon, Anksiyete, Renal replasman tedavileri, Beck depresyon ölçeği ABStrAct OBJEctIvE: Anxiety and depression are frequently observed among patients on renal replacement therapy (RRT). Our aim is to evaluate the frequency of depression and anxiety and their association with laboratory parameters, disease activity, performance status and sociodemographic properties of patients receiving hemodialysis (HD) or peritoneal dialysis (PD). mAtErIAl and mEthODS: Laboratory parameters and socio-demographic features of 77 patients on PD and 83 patients on HD were recorded. The psychological status of patients was evaluated with the Beck Anxiety-Depression Scale and the performance status was determined with the Karnofsky Scale.rESultS: There was no significant difference between the groups in terms of the frequency and severity of depression and anxiety. The percentage of patients with a university graduate degree, monthly income > 600 TL, and social insurance were significantly higher in the PD group (p<0.01). The frequency of depression was 2.66 times higher among female subjects p:0.02. In the HD group, the frequency of depression in patients with anxiety was 4.74 times higher than in patients without anxiety.cOncluSIOn: The present study showed that anxiety and depression are prevalent in patients receiving RRT and especially in female patients an...

Objective: In this study, the parameters of oxidative stress markers and thiol-disulfide homeostasis as a novel biomarker were evaluated in experimental groups of adult individuals, which were formed according to the body mass index (BMI). Materials and Methods: A total of 165 adult patients were grouped as normal weight (BMI 18.5-24.9, n=39), preobese or overweight (BMI 25-29.9, n=47), obese (BMI 30-34.9; n=44), and severely obese (BMI >35, n=35). In addition to thiol-disulfide homeostasis parameters, the total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), ischemia-modified albumin (IMA), albumin, and ceruloplasmin levels were determined. Results: Native thiol, total thiol, and native thiol/total thiol % levels were significantly decreased in the overweight, obese, and severely obese groups compared to the normal weight group (p<0.001). Disulfide levels were elevated in the overweight group compared to the normal weight group (p<0.01). While the TOS and OSI levels of the normal weight group were elevated compared to the overweight (p<0.001) and obese/severely obese groups (p<0.05), albumin levels of the normal weight group were reduced compared to other groups (p<0.001). The IMA levels of the overweight group were elevated compared to the normal weight and severely obese groups (p<0.05 and p<0.001, respectively). Ceruloplasmin levels of the severely obese group were increased compared to the normal weight and overweight groups (p<0.001 and p<0.01, respectively). Conclusion: In our study, oxidative stress was increased in groups with a BMI greater than normal (≥25). In addition to this, the oxidative stress and thiol-disulfide homeostasis markers are observed to be further increased in the overweight group than the obese (≥30) group due to body's reaction to first inconsistency.

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