Prostate cancer is a major global health issue and the second most common cause of cancer death in males in the developing world. 1 Better methods for patient stratification are urgently needed.Our understanding of the molecular pathology of prostate cancer is evolving fast, with advances in sequencing methods and bioinformatics. The Cancer Genome Atlas performed detailed molecular analysis on 333 primary prostate J.R. and C.V. contributed equally to this work.
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