Histamine is a biogenic amine, identified as a natural contaminant in food and alcoholic beverages, with high levels eliciting allergy-related conditions. Exposure to allergens can lead to abnormal high levels of histamine in the body that is detectable in blood and urine.A rapid histamine biosensor that can readily detect histamine levels in food, beverages and also be used as a diagnostic tool for allergy-related conditions will be an ideal point of care testing tool that is readily available at low cost. In addition, histamine has been identified as a close-range aggregation pheromone component in bed bug feces. Bed bug infestation has been on the rise in developed countries mainly in hotel, homes, shelters and school settings.A low cost, portable biosensor that readily detects bed bugs in these settings is in demand.Nano-aptamer based biosensors have previously been used to detect wide range of targets in medical diagnosis, agriculture, and industry. In this study, selected histamine-List of Tables .
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