Comparación del efecto in vitro de los aceites esenciales de Eucalyptus globulus y Origanum vulgare sobre Candida albicans aislada de paciente con candidiasis vulvovaginal Comparison of Eucalyptus globulus and Origanum vulgare essential oils' in vitro effect on Candida albicans isolated from a vulvo vaginal candidiasis patient
RESUMEN Objetivo: Evaluar la eficacia antifúngica del extracto etanólico de Eucalyptus globulus sobre Candida albicans in vitro. Material y Método: Se llevó a cabo un estudio analítico, transversal, experimental prospectivodurante 2018 en 60 placascon cepas de Candida albicansen la Universidad Nacional de Trujillo.La muestra, obtenida por fórmula, se dividió en 50 repeticiones para el grupo experimental y 10 para los controles. Resultados: La eficacia inhibitoria del extracto etanólico de Eucalyptus globulus sobre Cándida albicans no mostró diferencia estadística significativafrente al fluconazol (p>0.05). La concentración del extracto al 100% de pureza, en cuanto a susceptibilidad sobreCándida albicans,no mostró diferencia estadística significativa frente al fluconazol (p>0.05). Conclusiones: El extracto etanólico de Eucalyptus globulusmostró eficacia similar al fluconazol. La susceptibilidad del extracto también fue similar al fluconazol únicamente para la concentración al 100%. Palabras Clave: Cándida albicans,Eucalyptus globulus, eficacia. SUMMARY Objective: To evaluate the antifungal efficacy of the ethanolic extract of Eucalyptus globulus on Candida albicans in vitro. Material and Method: An analytical, cross-sectional, prospective experimental study was carried out during 2018 in 60 plates with strains of Candida albicans in the National University of Trujillo. The sample, obtained by formula, was divided into 50 repetitions for the experimental group and 10 for the controls. Results: The inhibitory efficacy of ethanolic extract of Eucalyptus globulus on C. albicans showed no significant statistical difference compared to fluconazole (p> 0.05). The concentration of the extract at 100% purity, in terms of susceptibility to Candida albicans, showed no significant statistical difference with fluconazole (p> 0.05). Conclusions: The ethanolic extract of Eucalyptus globulus showed efficacy similar to fluconazole. The susceptibility of the extract was also similar to fluconazole only for the 100% concentration.
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