2005. Differences in susceptibility between cattle and swamp buffaloes to infection with Fasciola gigantica. Tropical Animal Health and Production, 37(8), 611-616
The usual control for gastrointestinal parasites is the use of commercial anthelmintics. However, parasites are becoming more resistant due to the frequent and inappropriate use of these anthelmintics. As a result, alternatives for these anthelmintics are becoming increasingly widespread for deworming livestock, particularly those that come from natural sources. Thus, this study aimed to evaluate the efficacy of mango (var. Carabao) seed extract in reducing the egg per gram counts of common gastrointestinal nematodes in pigs and compare the efficacy with that of levamisole. Experimental animals were naturally infected pigs with Trichuris spp. and Strongyloides spp. being the most predominant. The animals were administered orally with a single dose of the mango seed extract at concentrations of 600, 700, and 800 mg per kg bodyweight. The extract, regardless of concentration, was able to decrease the epg counts. Within 14 days post-treatment, there was no significant difference in the efficacies in the administration of 800 mg extract per kg bodyweight and levamisole. This comparable efficacy was sustained until 28 days post-treatment. This significant in vivo anthelmintic activity may be attributed to the tannins and flavonoids present in the extract. These results indicate that the mango seed extract is effective in controlling and reducing the gastrointestinal nematodes in pigs and may have the potential to be further developed as an anthelmintic.
Objective:
This study aimed to determine the anticoccidial potential of
Tinospora rumphii
ethanolic stem extract, resulting in an effective reduction in oocysts per gram counts of
Eimeria
species in goats in comparison to the commercial coccidiostat toltrazuril.
Materials and Methods:
Eighteen goats that were naturally infected with coccidia were identified as experimental animals. The experimental animals were grouped and were administered a single dose of
T. rumphii
extract at concentrations of 300, 600, 1,000, and 2,000 mg extract/kg body weight. The fecal samples were collected before treatment, during the first treatment, and every week thereafter for 28 days posttreatment. Fecal examination was carried out using a modified McMaster technique to determine the oocysts per gram of feces, and the mean efficacies of the extracts were calculated.
Results:
Stem extracts of
T. rumphii
were able to lower the oocysts per gram count than pretreatment for all concentrations, but the efficacy, in general, was still lower than toltrazuril. A significant difference existed in the efficacy of the extracts among the treatments on day 14. Administering 1,000 mg/kg extract resulted in the highest efficacy rate (95.25%) at 14 days posttreatment and was comparable to that of toltrazuril (89.89%).
Conclusion:
The results show that the
T. rumphii
stem extract has the potential to reduce the
Eimeria
species oocysts per gram counts of naturally infected goats.
The treatment and prevention of coccidiosis in goats is costly to backyard farmers. It is for this reason that the use of alternative medicinal plants to treat coccidiosis are explored. Thus, this study aimed to determine the anticoccidial activity of the ethanol extract of C. aromaticus leaves. A total of 20 naturally coccidia-infected goats at the University of Southern Mindanao Goat Project served as experimental animals for the study. In relation to this, three concentrations of Coleus aromaticus extract were tested for anticoccidial activity: 600, 800, and 1000 mg extract/ kg bodyweight. The efficacies of these concentrations were determined and evaluated by comparing with a commercial coccidiostat, toltrazuril. It was found that 21 days post-treatment, the efficacies of the three extract concentrations were significant but was lower than toltrazuril. A significant difference (p = 0.0394) existed in the efficacies of the extracts among the treatments on day 21. The efficacy rate of administering 600 mg/kg extract (92.29%) was comparable to that of toltrazuril (96.65%) at 21 days post-treatment. This shows that the extract has the potential to be as effective as toltrazuril in reducing the oocyst per gram counts of naturally-infected goats.
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